Coexisting squamous cell carcinoma and high-grade neuroendocrine carcinoma, small cell type: a rare collision in cervix

BMJ Case Reports
Seema KaushalSunesh Kumar

Abstract

Collision tumours of the uterine cervix are extremely uncommon with exact incidence not known. Unlike squamous cell carcinoma (SCC) and adenocarcinoma that are known to coexist, small cell neuroendocrine carcinoma (SCNEC) is rarely documented with other histological types in the cervix. We report such rare case of a collision tumour in cervix displaying dual histological component of SCNEC and SCC in a 36-year-old woman. The case is being presented because of its rarity and represents a unique and hitherto seldom-reported combination of two malignant tumours with distinct and often contrasting epidemiology, histology and prognosis coexisting in the same patient.

References

Jan 1, 1991·The American Journal of Surgical Pathology·M H StolerA N Walker
Aug 28, 2003·British Journal of Cancer·R L M BekkersW J G Melchers
Sep 24, 2004·International Journal of Gynecological Pathology : Official Journal of the International Society of Gynecological Pathologists·Gabriela Mirei IshidaTeiichi Motoyama
Jun 3, 2008·Obstetrics and Gynecology·Jergin ChenDavid K Gaffney
Jul 8, 2014·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Kieran Walsh
Feb 14, 2016·Gynecologic Oncology·Benjamin MargolisJason D Wright

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