Abstract
Although coffee and green tea are suggested to reduce the risk of some types of cancers, only a few epidemiological studies have investigated their effect on the risk of acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS). Here, we investigated the association of coffee and green tea consumption and the risk of AML and MDS in a large-scale population-based cohort study in Japan. A total of 95,807 Japanese subjects (45,937 men and 49,870 women; age 40-69 years at baseline) were followed to the end of 2012, for an average of 18 years. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) for the association between coffee and green tea consumption at baseline and the risk of AML and MDS were assessed using a Cox proportional hazards model with adjustment for potential confounders. During 1,751.956 person-years, we identified 85 AML cases and 70 MDS cases. Our findings showed no significant association between coffee consumption and the risk of AML, or between green tea consumption and the risk of AML or MDS. In contrast, we observed a decreasing dose-response relationship between coffee consumption and the risk of MDS among men (almost none: reference, 1-4 times/week: HR = 0.83, 95% CI: 0.43-1.62; ≥1cups/day: HR...Continue Reading
References
Jun 18, 2002·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·C CavinB Schilter
Nov 4, 2004·American Journal of Epidemiology·Alberto AscherioMichael J Thun
Jun 24, 2005·Blood·Akira MatsudaMasao Tomonaga
May 9, 2006·Leukemia Research·Yulin LiSusan E McCann
May 13, 2006·Annals of Hematology·Tatjana PekmezovicNenad Brkic
Oct 25, 2007·Leukemia·J-J KiladjianA Caignard
Dec 19, 2007·British Journal of Cancer·M ZhangC D'Arcy J Holman
Jul 31, 2009·American Journal of Epidemiology·Toru NaganumaIchiro Tsuji
Nov 6, 2009·The New England Journal of Medicine·Ayalew Tefferi, James W Vardiman
Jan 1, 2010·American Journal of Epidemiology·Xiaomei MaAmanda J Cross
Jun 28, 2013·PloS One·Hongyan TongJie Jin
Nov 20, 2013·British Journal of Haematology·Dai ChiharaKeitaro Matsuo
Mar 29, 2014·Food & Function·Iziar A LudwigAlan Crozier
Apr 23, 2014·American Journal of Hematology·Sophia FircanisJorge J Castillo
Mar 1, 2011·Journal of Caffeine Research·Jennifer L Temple, Amanda M Ziegler
Aug 5, 2014·Journal of Epidemiology·Dai ChiharaKeitaro Matsuo
Aug 12, 2014·Japanese Journal of Clinical Oncology·Shoichiro Tsugane, Norie Sawada
Dec 23, 2014·Leukemia Research·Ping LiuC D'Arcy J Holman
Nov 5, 2015·Cancer Science·Takeshi MakiuchiShoichiro Tsugane
Nov 19, 2015·Genes & Nutrition·François GaaschtMarc Diederich
Nov 19, 2015·European Journal of Nutrition·Ping LiuC D'Arcy J Holman
Jan 14, 2016·Cancer Causes & Control : CCC·Stefano ParodiEmanuele Stagnaro
Jun 18, 2016·International Journal of Molecular Sciences·Andreas GlenthøjKirsten Grønbæk
Jul 2, 2016·Blood Cancer Journal·I De Kouchkovsky, M Abdul-Hay
Aug 26, 2016·International Journal of Cancer. Journal International Du Cancer·Takahiro OgawaUNKNOWN Japan Public Health Center-Based Prospective Study Group
Sep 27, 2016·Scientific Reports·Anqiang WangHaitao Zhao
Feb 6, 2017·Cancer Epidemiology·Stefano ParodiUNKNOWN Working Group for the Epidemiology of Hematolymphopoietic Malignancies in Italy
Citations
Jul 4, 2018·Leukemia & Lymphoma·Tomoyuki Kawada
Oct 28, 2019·Children·Vasantha H S Kumar, Steven E Lipshultz
Mar 3, 2020·The Cochrane Database of Systematic Reviews·Tommaso FilippiniMarco Vinceti
Aug 28, 2019·Cancer Causes & Control : CCC·Midori TakadaAkiko Tamakoshi
Mar 13, 2019·Cancer Cell International·Dongdong WuYanzhang Li
Oct 9, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Sumio HayakawaMamoru Isemura
Oct 20, 2020·Expert Opinion on Drug Metabolism & Toxicology·Tariq IsmailCarmela Fimognari