PMID: 2095747May 1, 1990Paper

Coffee consumption and blood pressure: a randomized, crossover clinical trial

Journal of General Internal Medicine
P C RosmarinG W Somes

Abstract

To examine the effect of moderate coffee consumption on blood pressure over a prolonged period of time. Previous work in this area has used primarily purified caffeine. A prospective, randomized, crossover clinical trial. A hypertension specialty outpatient clinic at the University of Tennessee, Memphis. Healthy, young, white men who were moderate coffee drinkers (less than 6 cups/day) were recruited. Twenty-four subjects were randomized and 21 (average age 35.5 years) completed the trial. Subjects were randomized to one of two groups: Group A drank three or more cups of coffee/day for two months, then crossed over to abstaining from coffee for two months; group B abstained from coffee first, then crossed over to drinking coffee. Only filter-brewed coffee was used. Subjects were seen at monthly intervals for blood pressure measurements. The average coffee consumption was 3.6 cups/day during the coffee-drinking phases. There was no difference between the coffee-drinking phase and the abstention phase in either systolic blood pressure (110.1 mmHg vs. 108.0 mmHg, respectively; 95% CI of difference -7.3, 2.5) or diastolic blood pressure (67.2 mmHg vs. 69.6 mmHg, respectively; 95% CI of difference -2.2, 6.4). Moderate daily consumpt...Continue Reading

References

Aug 10, 1978·The New England Journal of Medicine·C A BertrandI Micheli
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Citations

Apr 1, 1995·Psychopharmacology·S StreufertJ D Roache
Jan 1, 1991·Journal of General Internal Medicine·S Sweet
Mar 1, 1993·Pharmacology, Biochemistry, and Behavior·I Höfer, K Bättig
Aug 1, 1994·Pharmacology, Biochemistry, and Behavior·I Höfer, K Bättig
Nov 11, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Youyou ZhaoWeiguo Zhang
Sep 1, 1996·Annals of Behavioral Medicine : a Publication of the Society of Behavioral Medicine·P J GreenJ Suls

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