Coffee consumption and risk of coronary heart diseases: a meta-analysis of 21 prospective cohort studies

International Journal of Cardiology
Jiang-nan WuYu-ming Chen

Abstract

A large amount of cohort studies addressed coffee consumption and risk of coronary heart disease (CHD) and yielded inconsistent results. We conducted a meta-analysis to estimate the pooling effects. We searched for all published English articles indexed in MEDLINE or PubMed from January 1966 to January 2008. Twenty-one independent prospective cohort studies, which tested CHD risk by coffee consumption, were identified. A general variance-based method was used to pool the relative risks (RR). 15,599 cases from 407,806 participants were included in pooling the overall effects. As compared to the light coffee consumption (<1 cup/d in US or <or=2 cups/d in Europe), under the random-effects model, the pooled CHD RRs (95% CI) for all studies combined were 0.96 (0.87-1.06), 1.04 (0.92-1.17) and 1.07 (0.87-1.32) for the moderate (1-3 or 3-4 cups/d), heavy (4-5 or 5-6 cups/d) and very heavy (>or=6 or >or=7 cups/d) categories of coffee consumption (all p>0.05); Moderate coffee consumption showed significantly lower CHD RR (95% CI) of 0.82 (0.73-0.92) (p<0.001) in women, and of 0.87 (0.80-0.86) (p=0.001) in men and women followed <or=10 years. Our findings do not support the hypothesis that coffee consumption increases the long-term risk ...Continue Reading

Associated Clinical Trials

References

Aug 25, 1977·The New England Journal of Medicine·K YanoA Kagan
Sep 1, 1992·Archives of Internal Medicine·M G Myers, A Basinski
Mar 3, 1990·BMJ : British Medical Journal·A TverdalK Bjartveit
Oct 11, 1990·The New England Journal of Medicine·D E GrobbeeW Willett
Dec 1, 1989·International Journal of Epidemiology·S SalviniW C Willett
May 1, 1989·Archives of Internal Medicine·P W WilsonW P Castelli
Oct 16, 1986·The New England Journal of Medicine·A Z LaCroixT A Pearson
Jan 1, 1995·Journal of Internal Medicine·F GyntelbergH Sørensen
Jul 1, 1993·Journal of the American Dietetic Association·D FeskanichW C Willett
Mar 2, 1996·BMJ : British Medical Journal·I StensvoldB K Jacobsen
Feb 14, 1996·JAMA : the Journal of the American Medical Association·W C WillettC H Hennekens
Oct 6, 1997·BMJ : British Medical Journal·M EggerC Minder
Aug 1, 1997·Journal of Epidemiology and Community Health·C Hart, G D Smith
Jan 28, 1999·American Journal of Epidemiology·H D SessoC H Hennekens
Dec 9, 2000·Archives of Internal Medicine·P KleemolaJ Tuomilehto
Feb 24, 2001·American Journal of Epidemiology·S H JeeM J Klag
May 21, 2003·Journal of Internal Medicine·N HammarUNKNOWN SHEEP and the VHEEP study
Mar 11, 2004·JAMA : the Journal of the American Medical Association·Johan ArnlövUlf Risérus
Mar 11, 2004·JAMA : the Journal of the American Medical Association·Jaakko TuomilehtoPekka Jousilahti
Jul 7, 2005·JAMA : the Journal of the American Medical Association·Rob M van Dam, Frank B Hu
Mar 2, 2006·Critical Reviews in Food Science and Nutrition·Jane V Higdon, Balz Frei
Mar 9, 2006·JAMA : the Journal of the American Medical Association·Marilyn C CornelisHannia Campos
Dec 13, 2006·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Francesco SofiGian Franco Gensini
Dec 30, 2006·Circulation·Wayne RosamondUNKNOWN American Heart Association Statistics Committee and Stroke Statistics Subcommittee
Dec 20, 2007·Current Opinion in Clinical Nutrition and Metabolic Care·Marilyn C Cornelis, Ahmed El-Sohemy
Dec 3, 2008·International Journal of Cardiology·Andrew J S Coats

❮ Previous
Next ❯

Citations

May 12, 2010·The British Journal of Nutrition·Lina J LeursPiet A van den Brandt
Jul 19, 2013·European Journal of Clinical Nutrition·H UemuraK Arisawa
May 18, 2012·The New England Journal of Medicine·Neal D FreedmanRashmi Sinha
Jun 29, 2012·Circulation. Heart Failure·Elizabeth MostofskyMurray A Mittleman
Nov 28, 2013·The British Journal of Nutrition·Youjin Je, Edward Giovannucci
Aug 31, 2013·Current Cardiology Reports·Salome A Rebello, Rob M van Dam
Sep 17, 2011·American Journal of Epidemiology·Susanna C Larsson, Nicola Orsini
Jul 3, 2013·Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association·Vivian Ng, Sammy Saab
Dec 14, 2011·European Journal of Internal Medicine·Augusto Di CastelnuovoGiovanni de Gaetano
Mar 5, 2016·European Journal of Nutrition·Anthony ZulliPeter Kruzliak
Jan 7, 2016·Annual Review of Food Science and Technology·Candace DoepkerBrian T Welsh
Nov 29, 2015·American Journal of Epidemiology·Erikka LoftfieldRashmi Sinha
May 20, 2016·Journal of Clinical and Experimental Hepatology·Manav Wadhawan, Anil C Anand
Oct 23, 2012·Journal of Thrombosis and Haemostasis : JTH·R E J RoachW M Lijfering
Mar 31, 2015·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Giulia RendaRaffaele De Caterina
Mar 8, 2013·Maturitas·A Cano-MarquinaA Cano
Jul 23, 2013·Journal of the American College of Cardiology·James H O'KeefeCarl J Lavie
Jan 27, 2009·International Journal of Cardiology·Turgay CelikBasri Amasyali
Aug 28, 2016·International Journal of Cardiology·Konstantinos E PanagiotopoulosSavvas Toumanidis
Dec 26, 2012·Korean journal of family medicine·Byungsung KimChangwon Won
Jan 11, 2018·International Journal of Food Sciences and Nutrition·Nikolaos IoakeimidisDimitrios Tousoulis
Mar 12, 2011·Stroke; a Journal of Cerebral Circulation·Susanna C LarssonAlicja Wolk
Jan 28, 2016·Journal of the American Heart Association·Shalini DixitGregory M Marcus
Jun 22, 2010·Arteriosclerosis, Thrombosis, and Vascular Biology·J Margot de Koning GansJoline W J Beulens
Jan 8, 2019·Critical Reviews in Food Science and Nutrition·Muhammad SaeedSun Chao
Aug 31, 2010·European Journal of Gastroenterology & Hepatology·Gail Susan Masterton, Peter C Hayes
Sep 2, 2011·The American Journal of Clinical Nutrition·Arthur Eumann MesasEsther Lopez-Garcia
Mar 30, 2012·Food & Function·Siv K BøhnKevin D Croft
Oct 10, 2013·Liver International : Official Journal of the International Association for the Study of the Liver·Sammy SaabMyron J Tong
Mar 29, 2014·Food & Function·Iziar A LudwigAlan Crozier

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.