Coffee for Cardioprotection and Longevity

Progress in Cardiovascular Diseases
James H O'KeefeCarl J Lavie

Abstract

Coffee, a complex brew containing hundreds of biologically active compounds, exerts potent effects on long-term human health. Recently, a plethora of studies have been published focusing on health outcomes associated with coffee intake. An inverse association between coffee consumption and all-cause mortality has been seen consistently in large prospective studies. Habitual coffee consumption is also associated with lower risks for cardiovascular (CV) death and a variety of adverse CV outcomes, including coronary heart disease (CHD), congestive heart failure (HF), and stroke; coffee's effects on arrhythmias and hypertension are neutral. Coffee consumption is associated with improvements in some CV risk factors, including type 2 diabetes (T2D), depression, and obesity. Chronic coffee consumption also appears to protect against some neurodegenerative diseases, and is associated with improved asthma control, and lower risks for liver disease and cancer. Habitual intake of 3 to 4 cups of coffee appears to be safe and is associated with the most robust beneficial effects. However, most of the studies regarding coffee's health effects are based on observational data, with very few randomized controlled trials. Furthermore, the possib...Continue Reading

Citations

Oct 17, 2018·European Heart Journal·Vincenzo LionettiGrant N Pierce
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Apr 16, 2020·Critical Reviews in Food Science and Nutrition·Banafsheh Jafari AzadAndriko Palmowski
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Jun 4, 2020·Sensors·Paweł Piotr KonieczkaMiguel Palma
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