Coffee, Genetic Variants, and Parkinson's Disease: Gene-Environment Interactions

Journal of Caffeine Research
Naomi Yamada-Fowler, Peter Söderkvist

Abstract

Studies of gene-environment interactions may help us to understand the disease mechanisms of common and complex diseases such as Parkinson's disease (PD). Sporadic PD, the common form of PD, is thought to be a multifactorial disorder caused by combinations of multiple genetic factors and environmental or life-style exposures. Since one of the most extensively studied life-style factors in PD is coffee/caffeine intake, here, the studies of genetic polymorphisms with life-style interactions of sporadic PD are reviewed, focusing on coffee/caffeine intake.

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Citations

Aug 31, 2017·Critical Reviews in Food Science and Nutrition·Büşra Başar Gökcen, Nevin Şanlier
Sep 10, 2017·Movement Disorders : Official Journal of the Movement Disorder Society·J A ObesoA J Stoessl

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