Abstract
To determine cognitive and emotional changes among neurobrucellosis patients. The patients with neurobrucellosis and controls with brucellosis without neurologic involvement were included in the study. Neurobrucellosis was diagnosed by the following criteria: (i) symptoms or clinical findings compatible with neurobrucellosis, including headache, confusion, mental and emotional changes; (ii) isolation of Brucella spp. from CSF and/or demonstration of antibodies to Brucella > or = 1/4 in the CSF; (iii) the presence of lymphocytosis, increased protein and decreased glucose levels in the CSF; and (iv) clinical improvement with appropriate treatment. Two psychiatrists interviewed the patients, and performed the Hamilton Depression Rating Scale (HDRS) tests and Mini-Mental State Examination (MMSE) tests. Thirty-four neurobrucellosis cases and 30 patients with brucellosis without neurological involvement were studied. The mean age was 41 years, 12 (41%) patients were female, 13 (46%) patients were farmers, and 7 (25%) patients were housewives. Among the neurobrucellosis cases, before the antibiotic therapy, the mean MMSE test score was 21.6, one week after the therapy 22.7, and two weeks after the therapy 24.3 (p=0.024, and p<0.001, r...Continue Reading
Citations
Mar 1, 2013·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Tumer GuvenBasak Dokuzoguz
Dec 14, 2011·Antimicrobial Agents and Chemotherapy·Hakan ErdemHakan Leblebicioglu
Oct 5, 2010·The American Journal of Tropical Medicine and Hygiene·Katie M EalesNatkunam Ketheesan
Sep 1, 2009·Travel Medicine and Infectious Disease·E Van den EndenL Van den Hauwe
Oct 9, 2015·Neurology India·Ester ReggioMario Zappia
May 27, 2015·Journal of Clinical Pharmacy and Therapeutics·S JafariS Akhondzadeh
Jun 6, 2015·Clinical Therapeutics·Timothy Buie
May 12, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Hanefi Cem GulSemai Bek
Nov 17, 2009·International Journal of Infectious Diseases : IJID : Official Publication of the International Society for Infectious Diseases·Saime AySehim Kutlay
Nov 7, 2016·La Presse médicale·Inès FekiJaweher Masmoudi
Mar 29, 2018·BMJ Case Reports·Fatehi E ElzeinWassiem M Al-Hassan
Nov 28, 2007·Expert Review of Anti-infective Therapy·Georgios PappasLeonidas Christou
Mar 6, 2015·International Journal of MS Care·Kimberly Beckwith McGuireJohn DeLuca
Aug 29, 2020·Neurological Research·Ahmed EsmaelHosam Egilla
Apr 5, 2016·Metabolic Brain Disease·Hany M ElsheikhaXing-Quan Zhu
Dec 30, 2020·BMJ Case Reports·Harry Ross PowersJulio C Mendez
Nov 5, 2021·The Neurologist·Youssef BouferraaRosette Jabbour
May 3, 2008·Pediatrics·Mark W Shen