Cognitive and sensorimotor function in participants being treated for trigeminal neuralgia pain

The Journal of Headache and Pain
Rachel O CoatsMark Mon-Williams

Abstract

Trigeminal neuralgia (TN) is an orofacial condition defined by reoccurring, spontaneous, short-lived but excruciating stabbing pain. Pharmacological interventions constitute the first-line treatment for TN, with antiepileptic drugs commonly prescribed. People treated for TN pain with antiepileptic drugs describe cognitive and motor difficulties affecting activities of daily living, and report poorer quality of life. We undertook the first comprehensive objective evaluation of sensorimotor and cognitive performance in participants being treated for TN pain with antiepileptic drugs relative to age-matched controls. Participants (43 TN, 41 control) completed a battery of sensorimotor (steering, aiming and tracking) and cognitive (working memory, processing speed, inhibition) tasks. The TN group performed significantly worse than controls on the sensorimotor tracking and aiming tasks and across all cognitive measures. The data explain why patients treated with antiepileptic drugs report impairment when conducting activities of daily living (given the need for cognitive and motor capability within most of these). The study is an important first step in: (i) ensuring there is adequate information on the impact of pharmacological trea...Continue Reading

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Citations

Jun 27, 2021·British Dental Journal·Alice HamiltonEleni Besi

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Software Mentioned

JASP
Clinical Kinematic Assessment Tool ( CKAT )
SPSS
CKAT

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