Cognitive Behavioural Therapy for schizophrenia - outcomes for functioning, distress and quality of life: a meta-analysis

BMC Psychology
Keith R LawsSameer Jauhar

Abstract

The effect of cognitive behavioural therapy for psychosis (CBTp) on the core symptoms of schizophrenia has proven contentious, with current meta-analyses finding at most only small effects. However, it has been suggested that the effects of CBTp in areas other than psychotic symptoms are at least as important and potentially benefit from the intervention. We meta-analysed RCTs investigating the effectiveness of CBTp for functioning, distress and quality of life in individuals diagnosed with schizophrenia and related disorders. Data from 36 randomised controlled trials (RCTs) met our inclusion criteria- 27 assessing functioning (1579 participants); 8 for distress (465 participants); and 10 for quality of life (592 participants). The pooled effect size for functioning was small but significant for the end-of-trial (0.25: 95% CI: 0.14 to 0.33); however, this became non-significant at follow-up (0.10 [95%CI -0.07 to 0.26]). Although a small benefit of CBT was evident for reducing distress (0.37: 95%CI 0.05 to 0.69), this became nonsignificant when adjusted for possible publication bias (0.18: 95%CI -0.12 to 0.48). Finally, CBTp showed no benefit for improving quality of life (0.04: 95% CI: -0.12 to 0.19). CBTp has a small therapeut...Continue Reading

References

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Citations

Feb 14, 2019·Psychological Medicine·S JauharP J McKenna
Oct 30, 2019·Clinical Psychology & Psychotherapy·Johanna C BadcockGeorgie Paulik
Sep 10, 2019·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Pim Cuijpers
Sep 22, 2019·Social Psychiatry and Psychiatric Epidemiology·Karin C P RemmerswaalAnton J L M van Balkom
Jan 22, 2019·Psychotherapy Research : Journal of the Society for Psychotherapy Research·Louisa RobinsonStephen Kellett
May 24, 2019·Frontiers in Psychiatry·Roberto MediavillaMaria Fe Bravo-Ortiz
May 16, 2020·International Journal of Environmental Research and Public Health·Gabriele NibbioAntonio Vita
Jan 9, 2020·World Journal of Psychiatry·Keith R Laws, William Conway
Oct 20, 2020·Behavioural and Cognitive Psychotherapy·Daniel SilvaKatherine Newman-Taylor
Nov 26, 2020·Transcultural Psychiatry·Ross G WhiteSophia Xenophontos
Jan 4, 2021·European Archives of Psychiatry and Clinical Neuroscience·D KimhyM N Bartels
Dec 10, 2020·Heliyon·Rukhsana NawazFadwa Al Mughairbi
Jan 25, 2022·Behavioural and Cognitive Psychotherapy·Olivia PartridgeKatherine Newman-Taylor

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Methods Mentioned

BETA
Cognitive Behavioural Therapy

Software Mentioned

NICE
Comprehensive Meta - analysis
Scopus
PubMED

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