Cognitive Decline after Delirium in Patients Undergoing Cardiac Surgery

Anesthesiology
Charles H BrownCharles W Hogue

Abstract

Cardiac surgery is associated with cognitive decline and postoperative delirium. The relationship between postoperative delirium and cognitive decline after cardiac surgery is unclear The development of postoperative delirium is associated with a greater degree of cognitive decline 1 month after cardiac surgery. The development of postoperative delirium is not a predictor of cognitive decline 1 yr after cardiac surgery. Delirium is common after cardiac surgery and has been associated with morbidity, mortality, and cognitive decline. However, there are conflicting reports on the magnitude, trajectory, and domains of cognitive change that might be affected. The authors hypothesized that patients with delirium would experience greater cognitive decline at 1 month and 1 yr after cardiac surgery compared to those without delirium. Patients who underwent coronary artery bypass and/or valve surgery with cardiopulmonary bypass were eligible for this cohort study. Delirium was assessed with the Confusion Assessment Method. A neuropsychologic battery was administered before surgery, at 1 month, and at 1 yr later. Linear regression was used to examine the association between delirium and change in composite cognitive Z score from baseline...Continue Reading

Associated Clinical Trials

Sep 22, 2009·Charles W Hogue, Charles W Hogue

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Citations

Apr 18, 2019·Anesthesiology·Christina Boncyk, Christopher G Hughes
Apr 18, 2019·Anesthesiology·Charles H Brown, Charles W Hogue
Nov 26, 2019·Current Opinion in Anaesthesiology·Cynthia Olotu
Dec 14, 2019·Current Opinion in Anaesthesiology·Heiko A KaiserMichael S Avidan
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May 10, 2020·Anesthesia and Analgesia·Mitsunori NakanoCharles H Brown
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Mar 21, 2021·British Journal of Anaesthesia·Mitsunori NakanoCharles H Brown
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Sep 3, 2021·European Journal of Cardiovascular Nursing : Journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology·Hsiao-Wei ChengAi-Fu Chiou

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