Cognitive decline and alcohol consumption adjusting for functional status over a 3-year period in French speaking community living older adults

Journal of Public Health
Helen-Maria VasiliadisCarol Hudon

Abstract

The effect of alcohol consumption on cognitive decline is not clear. We aimed to study the association between alcohol consumption and cognitive functioning controlling for functional heath status. A total of 1610 older adults with a score ≥26 on the Mini-Mental State Examination (MMSE) were followed to assess the change in scores at the 3-year follow-up. Information on alcohol consumption as well as socio-demographic, lifestyle, psychosocial and clinical factors, as well as health service use were assessed at baseline and 3-year follow-up interviews. Linear mixed models with repeated measures were used stratifying by functional status. Close to 73% reported consuming alcohol in the past 6 months, of which 11% were heavy drinkers (≥11 and ≥16 drinks for women and men). A significant decrease in MMSE scores was observed in low functioning non-drinkers (-1.48; 95% CI: -2.06, -0.89) and light to moderate drinkers (-0.99; 95% CI: -1.54, -0.44) and high functioning non-drinkers (-0.51; 95% CI: -0.91, -0.10). Alcohol consumption did not contribute to cognitive decline. Cognitive decline was greater in individuals reporting low functional status. Research should focus on the interaction between changing patterns of alcohol consumption...Continue Reading

References

Nov 1, 1975·Journal of Psychiatric Research·M F FolsteinP R McHugh
Mar 1, 1981·Journal of Behavioral Medicine·A D KannerR S Lazarus
May 20, 2008·Age and Ageing·Ruth PetersChristopher Bulpitt
Dec 18, 2008·Canadian Journal of Psychiatry. Revue Canadienne De Psychiatrie·Michel PrévilleUNKNOWN Scientific Committee of the ESA Study
Jun 24, 2009·The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry·Kaarin J AnsteyNicolas Cherbuin
Nov 21, 2009·Canadian Journal on Aging = La Revue Canadienne Du Vieillissement·Carol HudonJoëlle Brassard
Aug 12, 2010·American Journal of Epidemiology·Elena LoboUNKNOWN ZARADEMP Workgroup
Aug 23, 2011·Neuropsychiatric Disease and Treatment·Edward J Neafsey, Michael A Collins
Mar 8, 2012·International Journal of Geriatric Psychiatry·Francesco PanzaVincenzo Solfrizzi
Sep 25, 2012·Ageing Research Reviews·Jana VolkertSylke Andreas
Jun 19, 2013·British Journal of Sports Medicine·Miriam WannerBrian W Martin
Jul 13, 2013·The British Journal of Psychiatry : the Journal of Mental Science·Gareth Hagger-JohnsonArchana Singh-Manoux
Sep 5, 2015·Current Clinical Pharmacology·Jenni IlomakiEija Lonnroos
Mar 25, 2017·Alcoholism, Clinical and Experimental Research·Rosalind A BreslowBarry I Graubard
Jul 4, 2017·Journal of Alzheimer's Disease : JAD·Erin L RichardLinda K McEvoy
Jan 18, 2018·Health and Quality of Life Outcomes·Helen-Maria Vasiliadis, Mathieu F Bélanger

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