Cognitive features 10 or more years after successful breast cancer survival: comparisons across types of cancer interventions.

Psycho-oncology
Christopher M NguyenSusan K Schultz

Abstract

The present study examined the long-term cognitive implications of cancer treatment among breast cancer survivors aged 65 years and older to better understand the long term implications of cancer treatment. Fifty-seven women survivors were compared with 30 healthy older female adult comparisons, matched in terms of age and education, with no history of cancer. Cancer survivors were also compared on the basis of treatment intervention, involving chemotherapy (n = 27) versus local therapy through surgery and radiation (n = 30). As a group, the breast cancer survivors scored lower on measures of general cognitive function, working memory, psychomotor speed, and executive function when compared with the normal comparisons. Among the cancer survivors, those who received local therapy scored lower than the other survivors and normal comparisons on measures of verbal learning, visual perception and construction, as well as visual attention and short-term retention. Our findings suggest that cognitive outcomes may involve greater age-related deficits among older cancer survivors compared with matched healthy subjects.

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Citations

Mar 25, 2014·Journal of the International Neuropsychological Society : JINS·Kim Edelstein, Lori J Bernstein
Jun 19, 2013·Critical Reviews in Oncology/hematology·Vincent KoppelmansSanne B Schagen
Nov 13, 2015·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·A M WilliamsE van Wijngaarden
Apr 15, 2014·Psycho-oncology·Lisa M JaremkaJanice K Kiecolt-Glaser
Apr 10, 2014·Cancer Treatment Reviews·Marie LangeFlorence Joly
Nov 8, 2018·Journal of the National Cancer Institute·Helena CarreiraKrishnan Bhaskaran
Dec 23, 2014·Journal of the International Neuropsychological Society : JINS·Myrle M Stouten-KempermanSanne B Schagen
Jul 15, 2017·Breast Cancer Research and Treatment·Christie YaoJill B Rich
Oct 9, 2020·Breast Cancer : the Journal of the Japanese Breast Cancer Society·Yen-Hsuan HsuMichael Gossop
Oct 21, 2020·Asia-Pacific Journal of Clinical Oncology·Miaomiao JiaJinnan Gao
Aug 10, 2021·Journal of Geriatric Oncology·Tim A AhlesArti Hurria

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