Cognitive Function in Individuals With Physical Frailty but Without Dementia or Cognitive Complaints: Results From the I-Lan Longitudinal Aging Study

Journal of the American Medical Directors Association
Yi-Hui WuLiang-Kung Chen

Abstract

To investigate if understated cognitive impairment existed in individuals with physical frail or earlier prefrail state but without cognitive complaints and the susceptible cognitive domains to the physical frailty. A cross-sectional population-based community study. I-Lan County of Taiwan. A total of 1839 community residents aged 50 years or older in the I-Lan Longitudinal Aging Study. None. Frail status assessments by the Cardiovascular Health Study (CHS) criteria and a series of neuropsychiatric assessments, including the Mini-Mental State Examination (MMSE), the delay free recall in the Chinese Version Verbal Learning Test (CVVLT), the Boston Naming Test (BNT), the category (animal) Verbal Fluency Test (VFT), the Taylor Complex Figure Test (CFT), the digital backward (DB), and the Clock Drawing Test. After excluding those with significant global cognitive impairment, subjective cognitive complaints, or functional impairment, 1686 persons aged 50 to 89 years (mean 63.4 ± 8.9) were enrolled. The prevalence of prefrail and frail individuals was 40.2% and 4.9%, respectively. The prefrail and frail persons had significantly poorer performance in the MMSE and all neuropsychological tests. Slowness and weakness were the most signi...Continue Reading

References

Feb 1, 1995·Journal of the American Geriatrics Society·H C LiuB N Chiang
Mar 1, 1997·Stroke; a Journal of Cerebral Circulation·S D KantersJ D Banga
Jul 15, 2000·The British Journal of Clinical Psychology·J E HarrisonR Wise
Mar 17, 2001·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·L P FriedUNKNOWN Cardiovascular Health Study Collaborative Research Group
Aug 26, 2004·Journal of the International Neuropsychological Society : JINS·Robert L HesterBen Ong
Jul 20, 2007·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kenneth RockwoodArnold Mitnitski
Feb 28, 2009·Journal of the American Geriatrics Society·José Alberto Avila-FunesJean-François Dartigues
Jan 15, 2010·Journal of the American Geriatrics Society·Patricia A BoyleDavid A Bennett
Feb 16, 2010·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Catherine J Stoodley, Jeremy D Schmahmann
Aug 11, 2010·Archives of Neurology·Teresa BuracchioJeffrey Kaye
Nov 26, 2010·Clinics in Geriatric Medicine·Qian-Li Xue
May 5, 2011·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·Peter Crome, Frank Lally
Nov 22, 2011·Journal of Nutrition in Gerontology and Geriatrics·Roschelle A Heuberger
Sep 19, 2012·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Joe VergheseRoee Holtzer
Oct 6, 2012·The Journal of Neuropsychiatry and Clinical Neurosciences·Donald EknoyanKatherine H Taber
Jul 9, 2013·Ageing Research Reviews·Deirdre A RobertsonRose Anne Kenny
Nov 14, 2013·PloS One·Haobo ZhangJulian N Trollor
Jun 23, 2015·Human Brain Mapping·Wei-Ta ChenChing-Po Lin

❮ Previous
Next ❯

Citations

May 29, 2016·Journal of the American Medical Directors Association·John E Morley
Jun 22, 2016·PeerJ·Chia-Ter ChaoUNKNOWN COGENT (COhort of GEriatric Nephrology in NTUH) study group
Aug 1, 2016·Journal of the American Medical Directors Association·John E Morley, Susan A Farr
Sep 28, 2016·Wiener klinische Wochenschrift·John E Morley
Mar 2, 2017·Journal of the American Geriatrics Society·Catharine R GaleIan J Deary
May 17, 2019·Journal of the American Geriatrics Society·Katherine A GiffordAngela L Jefferson
Jun 22, 2019·Alzheimer's Research & Therapy·Sherilyn ThibeauRoger A Dixon
Jun 20, 2020·Journal of Cachexia, Sarcopenia and Muscle·Shih-Tsung HuangLiang-Kung Chen
Nov 30, 2019·Translational Psychiatry·Anna J StevensonRiccardo E Marioni
Feb 20, 2020·Arquivos de neuro-psiquiatria·Allan Gustavo BrigolaSofia Cristina Iost Pavarini
May 1, 2019·International Journal of Environmental Research and Public Health·Miji Kim, Chang Won Won
Apr 21, 2020·BMC Geriatrics·Sonia HammamiVeronique Latteur
Jul 22, 2020·Journal of the American Medical Directors Association·Osamu KatayamaHiroyuki Shimada
Nov 27, 2020·Frontiers in Medicine·Laura Lorenzo-LópezJosé Carlos Millán-Calenti
Jan 6, 2021·Alzheimer's Research & Therapy·Linzy BohnRoger A Dixon
May 11, 2020·Journal of the American Medical Directors Association·Claire Leissing-DesprezSylvie Bastuji-Garin
Feb 6, 2020·Arquivos de neuro-psiquiatria·Allan Gustavo BrigolaSofia Cristina Iost Pavarini
Mar 26, 2021·Archives of Gerontology and Geriatrics·Chih-Kuang LiangLiang-Kung Chen
Oct 31, 2017·Journal of the American Medical Directors Association·Barbara J Messinger-RapportJulie K Gammack
Aug 20, 2021·Frontiers in Aging Neuroscience·Yi-Chia WeiChing-Po Lin

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Cardiovascular Disorder in Diabetes

Diabetes is associated with an increased risk of cardiovascular disorders and heart failure. Discover the latest research here.

Alzheimer's Disease: Neuroimaging

Neuroimaging can help identify pathological hallmarks of Alzheimer's disease (AD). Here is the latest research on neuroimaging modalities, including magnetic resonance imaging and positron emission tomography, in AD.