Cognitive impairment associated with schizophrenia: a review of the humanistic burden

Advances in Therapy
Helen KitchenPat Sacco

Abstract

Nearly every individual with schizophrenia is affected by cognitive decline. The aim of this literature review was to: (a) describe the humanistic burden of cognitive impairment associated with schizophrenia (CIAS); (b) develop a conceptual model that depicts the signs and symptoms of CIAS along with key concepts important to patients; and (c) consider the adequacy of potential patient-reported outcome (PRO) instruments for assessing future treatments. The following electronic databases were searched for articles published between January 1999 and November 2009 related to CIAS and PROs, or cost of illness: Medline; Embase; PsycINFO; the Health Economic Evaluation Database; and the National Health Service Economic Evaluation Database and Health Technology Assessment databases at the Centre for Reviews and Dissemination, University of York. The literature search revealed 3950 abstracts, of which 101 articles were reviewed in detail. Cognitive functions affected include memory, attention/concentration, problem solving, learning, executive function, processing speed, and social cognition. Cognitive impairment impacts the ability of individuals to carry out activities of daily living, work productively, function socially, and adhere...Continue Reading

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Citations

Sep 13, 2013·Future Medicinal Chemistry·Abraham LópezErnest Giralt
Jul 17, 2013·Asia-Pacific Psychiatry : Official Journal of the Pacific Rim College of Psychiatrists·A Talib NorlelawatiAbdul Razak Tariq
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Jun 11, 2020·Translational Psychiatry·Suhua ChangStephen V Faraone
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Sep 2, 2020·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Jason M Noel, Cherry W Jackson
Nov 26, 2021·Neuroscience and Biobehavioral Reviews·Marianne KhalilKatie M Lavigne

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