PMID: 3769569Nov 1, 1986Paper

Cognitive impairment in patients with obstructive sleep apnea and associated hypoxemia

Chest
L J FindleyP M Suratt

Abstract

Twenty-six patients with sleep apnea had neuropsychologic testing prior to nocturnal sleep study in a sleep disorders clinic. The cognitive functioning of patients who had sleep apnea with associated hypoxemia was compared to nonhypoxemic patients with sleep apnea. The patients who had sleep apnea with hypoxemia had more severe cognitive impairment than those with sleep apnea without hypoxemia. The hypoxemic patients with sleep apnea had significantly poorer cognitive functioning on four of eight tests (p less than 0.05). In addition, the patients who had sleep apnea with hypoxemia had mean performance scores in the impaired range on measures of attention, concentration, complex problem-solving, and short-term recall of verbal and spatial information. In contrast, the patients who had sleep apnea without hypoxemia had no mean performance score in the impaired range. The degree of hypoxemia during sleep and wakefulness significantly correlated with the degree of overall cognitive impairment as rated by a neuropsychologist; however, measures of sleep fragmentation did not significantly correlate with overall cognitive impairment in patients with sleep apnea. We conclude that patients who have sleep apnea with associated hypoxemia...Continue Reading

References

Dec 1, 1976·Annals of Internal Medicine·A G TilkianW C Dement
Jan 1, 1985·Respiration; International Review of Thoracic Diseases·S C WilhoitD L Kaiser
Jan 1, 1984·Computer Programs in Biomedicine·R J EvansP M Suratt
Nov 1, 1956·The American Journal of Medicine·A G BICKELMANNR D WHALEY

❮ Previous
Next ❯

Citations

Jan 1, 1993·New Directions for Mental Health Services·K Dogramji
Nov 14, 1997·Clinical Reviews in Allergy & Immunology·P N Lao
Mar 31, 2005·Neuropsychology Review·Javier Virués-OrtegaBernardino Alcázar
Feb 28, 2002·Sleep & Breathing = Schlaf & Atmung·S A ChungC M Shapiro
Feb 7, 2007·Sleep & Breathing = Schlaf & Atmung·Mónica de la Peña BravoDavid Gozal
Oct 2, 2007·Sleep & Breathing = Schlaf & Atmung·Manos AlchanatisCharis Roussos
Feb 23, 2010·Sleep & Breathing = Schlaf & Atmung·Athanasios G XiromeritisNikiforos V Angelopoulos
Sep 8, 2011·Sleep & Breathing = Schlaf & Atmung·Isaac ShpirerMichael Khaigrekht
Oct 16, 2012·Sleep & Breathing = Schlaf & Atmung·Karin F HothMark S Aloia
Apr 29, 2010·Current Neurology and Neuroscience Reports·Diane C Lim, Sigrid C Veasey
Nov 16, 1995·Biological Psychology·P J VosC L van Herwaarden
Dec 4, 2004·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Charles S Ebert, Amelia F Drake
Jun 7, 2005·Primary Care·Alon Y Avidan
Jul 20, 2002·Journal of Psychosomatic Research·Donald L Bliwise
Aug 22, 1987·Lancet·C F GeorgeM H Kryger
Jul 30, 2003·Neurobiology of Aging·Masayuki KambaYuji Suto
Mar 10, 2001·Biological Psychology·S K Lal, A Craig
Aug 18, 2004·Sleep Medicine Reviews·H Engleman, D Joffe
Jun 1, 2000·Sleep Medicine·J M ParishJ Wisbey
Jul 1, 1996·Journal of the International Neuropsychological Society : JINS·E VerstraetenJ De Roeck
Jan 24, 2004·Journal of the International Neuropsychological Society : JINS·Kris L KaemingkStuart F Quan
Jan 31, 2004·Journal of the International Neuropsychological Society : JINS·Shawn D Gale, Ramona O Hopkins
Aug 26, 2004·Journal of the International Neuropsychological Society : JINS·Mark S AloiaDesiree Byrd
Apr 2, 2005·Journal of the International Neuropsychological Society : JINS·Ramona O Hopkins, Kathleen Y Haaland
May 12, 2001·Journal of the American Geriatrics Society·O SandbergY Gustafson
Feb 15, 2002·Journal of the American Geriatrics Society·M Cohen-ZionS Ancoli-Israel
Mar 1, 1989·Journal of Clinical and Experimental Neuropsychology·D T BerryB C Prine
Nov 1, 1991·Journal of Clinical and Experimental Neuropsychology·M A BédardJ Malo
Sep 14, 2007·Journal of Clinical and Experimental Neuropsychology·Agnès DauratMichel Tiberge
Apr 14, 2006·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Terri BlackwellUNKNOWN Study of Osteoporotic Fractures Group
Jan 1, 1997·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·A NodaM Yokota
Sep 1, 1995·Journal of Sleep Research·I E Smith, J M Shneerson

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.