Cognitive impairment in survivors of out-of-hospital cardiac arrest

American Heart Journal
Anouk P van AlemR W Koster

Abstract

The huge importance of rapid provision of care, especially early defibrillation, for survival of out-of-hospital cardiac arrest (OHCA) is well known. This prospective cohort study investigated cognitive functioning of OHCA survivors in relation to the time-related elements of the resuscitation. Fifty-seven consecutive survivors, from a cohort of 308 witnessed OHCA patients with ventricular fibrillation as the initial rhythm, underwent extensive neuropsychologic examination, including tests of memory, attention, and executive functioning, 6 months after the resuscitation. Time-related aspects of the resuscitation were collected on scene. Cognitive functioning was studied in relation to the administration of cardiopulmonary resuscitation (CPR) prior to ambulance arrival, and time from collapse to start of CPR, defibrillation, and return of spontaneous circulation (ROSC). Depending of the test, between 11% and 28% of survivors were cognitively impaired, while 58% scored unimpaired for all tests. Daily life activities were limited in 19% of the patients. Patients who received CPR prior to arrival of the ambulance showed a trend towards overall better cognitive functioning and significant better immediate memory and visuomotor track...Continue Reading

References

Jan 13, 1993·JAMA : the Journal of the American Medical Association·R O RoineM Kaste
Jul 20, 1996·BMJ : British Medical Journal·N R GrubbK A Fox
Feb 16, 1999·Archives of Internal Medicine·R de VosR J de Haan
Sep 17, 1999·Resuscitation·J HerlitzG Thorgeirsson

❮ Previous
Next ❯

Citations

Sep 23, 2006·Der Anaesthesist·A SchneiderB W Böttiger
Jan 7, 2011·Journal of the International Neuropsychological Society : JINS·Michael P AlexanderMieke Verfaellie
Sep 2, 2011·The New England Journal of Medicine·Ian G StiellUNKNOWN ROC Investigators
Apr 24, 2008·Critical Care Medicine·Michael FriesRolf Rossaint
Mar 13, 2010·Southern Medical Journal·Christopher H Lee, David C Cone
Oct 5, 2011·Circulation·Lance B BeckerUNKNOWN Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation
Apr 26, 2006·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Jerris R HedgesUNKNOWN Public Access Defibrillation Trial Investigators
Feb 20, 2009·Anesthesia and Analgesia·Andreas SchneiderErik Popp
Jul 11, 2014·Therapeutic Hypothermia and Temperature Management·Stephen IannaconeBenjamin S Abella
Sep 17, 2014·The American Journal of Emergency Medicine·Mathias StröhleHermann Brugger
Nov 14, 2008·Brain Injury : [BI]·C HofgrenK S Sunnerhagen
Jan 31, 2016·Resuscitation·Mary Ann PeberdyUNKNOWN National Post Arrest Research Consortium (NPARC) Investigators
Apr 2, 2013·The American Journal of Emergency Medicine·Christopher K MehtaWilliam J Brady
Aug 25, 2009·American Heart Journal·Jonas S S G de JongLukas R C Dekker
Apr 30, 2014·Critical Care Medicine·Michael W DonninoUNKNOWN National Post-Arrest Research Consortium
Jan 2, 2009·Resuscitation·Véronique R M P MoulaertDerick T Wade
Apr 24, 2007·Resuscitation·Markus AlbertsmeierBernd W Böttiger
Mar 20, 2010·Acta Anaesthesiologica Scandinavica·J TorgersenH Flaatten
Oct 1, 2015·BioMed Research International·Ketki D RainaClifton W Callaway
May 31, 2015·Resuscitation·Graham NicholUNKNOWN Resuscitation Outcomes Consortium Investigators
Jan 10, 2012·Journal of Critical Care·Hayley B GershengornHannah Wunsch
Mar 5, 2015·Resuscitation·Alexa R SabedraUNKNOWN Post Cardiac Arrest Service

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.