Cognitive neuroscience using wearable magnetometer arrays: Non-invasive assessment of language function.

NeuroImage
Tim M TierneyGareth R Barnes

Abstract

Recent work has demonstrated that Optically Pumped Magnetometers (OPMs) can be utilised to create a wearable Magnetoencephalography (MEG) system that is motion robust. In this study, we use this system to map eloquent cortex using a clinically validated language lateralisation paradigm (covert verb generation: 120 trials, ∼10 min total duration) in healthy adults (n = 3). We show that it is possible to lateralise and localise language function on a case by case basis using this system. Specifically, we show that at a sensor and source level we can reliably detect a lateralising beta band (15-30 Hz) desynchronization in all subjects. This is the first study of human cognition using OPMs and not only highlights this technology's utility as tool for (developmental) cognitive neuroscience but also its potential to contribute to surgical planning via mapping of eloquent cortex, especially in young children.

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Citations

Mar 1, 2020·Annals of Clinical and Translational Neurology·Umesh VivekanandaMatthew C Walker
Nov 7, 2019·Nature Communications·Ryan M HillMatthew J Brookes
Jul 12, 2019·Human Brain Mapping·Leonardo Duque-MuñozGareth R Barnes
Oct 16, 2020·NeuroImage·Tim M TierneyGareth R Barnes
Dec 12, 2020·Scientific Reports·Tim M TierneyGareth R Barnes
Feb 2, 2021·NeuroImage·Elena BotoMatthew J Brookes
Mar 22, 2021·NeuroImage·Paul de LangeMathieu Bourguignon
Jul 4, 2021·Neurologic Clinics·Elaine S Seto, Rohini Coorg
Aug 12, 2021·BMC Biology·Benjamin WittevrongelMatthew J Brookes
Sep 4, 2021·Scientific Reports·George C O'NeillGareth R Barnes
Sep 24, 2021·NeuroImage·Robert A SeymourEleanor A Maguire
Jun 8, 2019·NeuroImage·Gillian RobertsMatthew J Brookes
Oct 24, 2020·Seizure : the Journal of the British Epilepsy Association·Umesh Vivekananda
Jan 20, 2022·PloS One·Urban MarhlVojko Jazbinšek

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Methods Mentioned

BETA
imaging technique

Software Mentioned

DAiSS
Matlab
SPM12

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