Cognitive predictors of understanding treatment decisions in patients with newly diagnosed brain metastasis

Cancer
Adam GersteneckerKristen Triebel

Abstract

Medical decision-making capacity is a higher-order functional skill that refers to a patient's ability to make informed, sound decisions related to care and treatment. In a medical context, understanding is the most cognitively demanding consent standard and refers to a patient's ability to comprehend information to the extent that informed decisions can be made. The association between reasoning and cognition was examined using data from 41 patients with diagnosed brain metastasis. All diagnoses were made by a board-certified radiation oncologist and were verified histologically. In total, 41 demographically matched, cognitively healthy controls were also included to aid in classifying patients with brain metastasis according to reasoning status (ie, intact or impaired). Results indicate that measures of simple attention, verbal fluency, verbal memory, processing speed, and executive functioning were all associated with understanding, and that verbal memory and phonemic fluency were the primary cognitive predictors. Using these two primary predictors, equations can be constructed to predict the ability to understand treatment decisions in patients with brain metastasis. Although preliminary, these data demonstrate how cognitiv...Continue Reading

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Citations

Aug 24, 2016·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Barton W Palmer, Alexandrea L Harmell
Jul 8, 2015·Journal of the International Neuropsychological Society : JINS·Adam GersteneckerKristen L Triebel
May 3, 2019·Current Oncology Reports·Will HewinsRobin Grant
Dec 15, 2020·Neuro-oncology Practice·Andrea PaceLinda Dirven
Jan 20, 2021·Psycho-oncology·Adam GersteneckerKristen Triebel
Feb 4, 2021·Clinical Oncology : a Journal of the Royal College of Radiologists·W C M SchimmelK Gehring
Mar 16, 2021·Dose-response : a Publication of International Hormesis Society·Yue HuangNaiyao Chen
Nov 24, 2021·Acta Anaesthesiologica Scandinavica·Richard A BuckleyLisbeth Evered

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