Cognitive rehabilitation of mildly impaired Alzheimer disease patients on cholinesterase inhibitors

The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
David A LoewensteinRanjan Duara

Abstract

The authors evaluated the efficacy of a new cognitive rehabilitation program on memory and functional performance of mildly impaired Alzheimer disease (AD) patients receiving a cholinesterase inhibitor. Twenty-five participants in the Cognitive Rehabilitation (CR) condition participated in two 45-minute sessions twice per week for 24 total sessions. CR training included face-name association tasks, object recall training, functional tasks (e.g., making change, paying bills), orientation to time and place, visuo-motor speed of processing, and the use of a memory notebook. Nineteen participants in the Mental Stimulation (MS) condition had equivalent therapist contact and number of sessions, which consisted of interactive computer games involving memory, concentration, and problem-solving skills. Compared with the MS condition, participants in CR demonstrated improved performance on tasks that were similar to those used in training. Gains in recall of face-name associations, orientation, cognitive processing speed, and specific functional tasks were present post-intervention and at a 3-month follow-up. A systematic program of cognitive rehabilitation can result in maintained improvement in performance on specific cognitive and fun...Continue Reading

Citations

Aug 5, 2006·Proceedings of the National Academy of Sciences of the United States of America·Henry W MahnckeMichael M Merzenich
Jun 14, 2006·Psychology and Aging·Roger RatcliffGail McKoon
May 6, 2008·American Journal of Alzheimer's Disease and Other Dementias·Sandy C BurgenerSara Marsh-Yant
May 15, 2008·BMC Family Practice·Patrizio PezzottiUNKNOWN Progetto Alzheimer Working Group
Oct 29, 2008·American Journal of Alzheimer's Disease and Other Dementias·Melanie C GreenawayGlenn E Smith
Feb 27, 2009·Journal of the International Neuropsychological Society : JINS·Leslie J Gonzalez RothiStephen E Nadeau
Oct 9, 2009·Alzheimer Disease and Associated Disorders·Deborah E BarnesJoel H Kramer
Sep 29, 2011·BMC Geriatrics·Nicola J GatesMichael Valenzuela
Oct 7, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Jonathan P RoiserBarbara J Sahakian
Aug 8, 2007·Psychological Science·David Bissig, Cindy Lustig
Sep 4, 2008·Journal of the International Neuropsychological Society : JINS·Benjamin M HampsteadAnthony Y Stringer
Feb 19, 2008·Rejuvenation Research·Raffaele Antonelli IncalziFranco Rengo
Jun 2, 2009·Brain : a Journal of Neurology·Liselore SnaphaanFrank-Erik de Leeuw
Jul 14, 2006·Acta Psychiatrica Scandinavica·D I SitzerD V Jeste
May 26, 2006·Journal of Advanced Nursing·Kader ParahooDeborah Nusbaum
Dec 13, 2012·IEEE Reviews in Biomedical Engineering·Adriana M SeelyeDiane J Cook
Sep 12, 2013·Dementia and Geriatric Cognitive Disorders·Carme CarrionAbel López-Bermejo
Nov 28, 2012·Dementia and Geriatric Cognitive Disorders·Aimee SpectorLouise Hall
Jul 30, 2005·World Journal of Gastroenterology : WJG·Shan-Zhi GuBo-Rong Pan
Jun 9, 2012·International Journal of Geriatric Psychiatry·M C GreenawayG E Smith
Nov 19, 2011·Expert Review of Neurotherapeutics·Rose-Marie DröesFranka J M Meiland
Oct 1, 2007·Alzheimer's & Dementia : the Journal of the Alzheimer's Association·David B HoganLilian Thorpe
Jun 21, 2013·Aging Clinical and Experimental Research·Susanna BergamaschiSara Mondini
Mar 3, 2015·Journal of Physical Therapy Science·Seyun Kim
Dec 18, 2020·Frontiers in Aging Neuroscience·Xin-Tong SuCun-Zhi Liu

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Trends in Ecology & Evolution
J May
American Journal of Alzheimer's Disease and Other Dementias
Tiziana MaciMario Zappia
The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Kaisu H PitkalaReijo S Tilvis
Trends in Ecology & Evolution
B Charlesworth
The American Journal of Geriatric Psychiatry : Official Journal of the American Association for Geriatric Psychiatry
Linda ClareMichael D Rugg
© 2022 Meta ULC. All rights reserved