PMID: 15224870Jul 1, 2004Paper

Cognitive tinnitus sensitization: behavioral and neurophysiological aspects of tinnitus centralization

Acta Oto-laryngologica
Hans-Peter Zenner, Ilse M Zalaman

Abstract

Acquired centralized tinnitus (ACT) is the most frequent type of chronic tinnitus. We introduce a cognitive neurophysiological ACT hypothesis based on centralized cognitive sensitization processes. Published cognitive sensitization processes were reviewed using PubMed. Furthermore, a Cochrane analysis was performed. Patients frequently perceive tinnitus as being extremely loud although audiological tinnitus-matching measures reveal that its loudness levels are low. An important principle of central tinnitus processing is that individual tinnitus appraisal is directly linked to neuronal networks in the brain responsible for the production of emotions and cognitions. Cognitive processes may be associated with a reduction in the tinnitus cognition threshold, resulting in hypersensitivity of cognition. The underlying mechanism is known as sensitization and is suggested to be a specific learning process. ACT may be associated with a specific learning process allowing increased tinnitus awareness and continuous appraisal. The underlying mechanism, the cognitive tinnitus sensitization process, is associated with a decrease in the tinnitus cognition threshold. The sensitization contributes to the extremely loud cognition of the tinnitu...Continue Reading

Citations

Mar 15, 2011·Ear and Hearing·Rilana F F CimaJohan W S Vlaeyen
Jul 24, 2010·International Journal of Otolaryngology·Francesco MartinesGioacchino Martinciglio
Mar 4, 2006·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·D Alpini, A Cesarani
Jan 1, 2011·Case Reports in Psychiatry·Robert L FolmerSarah Theodoroff
Jul 12, 2012·Experimental Brain Research·Sven VannesteDirk De Ridder
Dec 16, 2005·Acta Oto-laryngologica·H Peter Zenner, Harry De Maddalena
May 10, 2007·International Journal of Audiology·Catherine StevensMelinda Gallagher
Aug 28, 2014·BioMed Research International·Yiwen ZhengPaul F Smith
Mar 23, 2012·Medical Hypotheses·Michael A Kadoch
Oct 25, 2007·Progress in Brain Research·P J Jastreboff
Nov 30, 2006·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Hans P ZennerNiels Birbaumer
Nov 23, 2006·Acta Oto-laryngologica. Supplementum·Gerhard Andersson, Laurence McKenna

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