Cohort Study of Carbon Black Exposure and Risk of Malignant and Nonmalignant Respiratory Disease Mortality in the US Carbon Black Industry

Journal of Occupational and Environmental Medicine
Linda D DellKenneth A Mundt

Abstract

To evaluate lung cancer and respiratory disease mortality associations with cumulative inhalable carbon black exposure among 6634 US carbon black workers. This analysis was performed using standardized mortality ratio (SMRs) and Cox regression analyses. Lung cancer mortality was decreased overall (SMR = 0.77; 95% confidence interval [CI], 0.67 to 0.89) but less so among hourly male workers (SMR = 0.87; 95% CI, 0.71 to 1.05). No exposure-response association was observed with time-dependent cumulative inhalable carbon black: hazard ratio [HR] = 1.0 (95% CI, 0.6 to 1.6) for 20 to less than 50 mg/m·yr); HR = 1.3 (95% CI, 0.8 to 2.1) for 50 to less than 100 mg/m·yr; and HR = 1.4 (95% CI, 0.9 to 2.1) for 100 mg/m·yr or more compared with referent (<20 mg/m·yr). No consistent associations were observed between cumulative inhalable carbon black exposure and respiratory disease mortality. Quantitative carbon black exposure estimates were not related to lung cancer or nonmalignant respiratory disease mortality.

References

Oct 1, 1989·American Industrial Hygiene Association Journal·J M Robertson, T H Ingalls
Dec 1, 1982·American Industrial Hygiene Association Journal·R G Smith, D C Musch
May 1, 1980·Archives of Environmental Health·J M Robertson, T H Ingalls
Jun 1, 1996·Journal of Occupational and Environmental Medicine·J M Robertson, K J Inman
Feb 15, 2001·American Journal of Industrial Medicine·T SorahanJ M Harrington
Sep 6, 2002·The European Respiratory Journal·M J A van TongerenM J Harrington
Oct 5, 2002·Applied Occupational and Environmental Hygiene·Steven M KerrJames H Vincent
Mar 11, 2003·Journal of Occupational and Environmental Medicine·Philip HarberBrenda Merz
Feb 25, 2006·Occupational and Environmental Medicine·J WellmannK Straif
Dec 13, 2006·Journal of Occupational and Environmental Medicine·Linda D DellUNKNOWN International Carbon Black Association
Dec 13, 2006·Journal of Occupational and Environmental Medicine·Peter MorfeldClaus Piekarski
Dec 13, 2006·Journal of Occupational and Environmental Medicine·Sebastian F BüchteUNKNOWN International Carbon Black Association
Dec 13, 2006·Journal of Occupational and Environmental Medicine·Peter MorfeldUNKNOWN International Carbon Black Association
May 23, 2007·American Journal of Industrial Medicine·Tom Sorahan, J Malcolm Harrington
Jul 11, 2007·American Journal of Industrial Medicine·Peter Morfeld, Robert J McCunney
Sep 16, 2009·American Journal of Industrial Medicine·Peter Morfeld, Robert J McCunney
Aug 13, 2010·Journal of Occupational Medicine and Toxicology·Peter Morfeld, Robert J McCunney
Jun 26, 2012·Chemical Research in Toxicology·Len LevyRobert J McCunney

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Citations

Mar 24, 2016·International Journal of Environmental Research and Public Health·Peter MorfeldRobert J McCunney
Sep 13, 2019·Journal of Occupational and Environmental Medicine·Mei YongRobert J McCunney
Dec 31, 2015·Journal of Occupational and Environmental Medicine·Peter Morfeld
Dec 31, 2015·Journal of Occupational and Environmental Medicine·Linda D DellKenneth A Mundt
Nov 3, 2017·Critical Reviews in Toxicology·Ishrat ChaudhuriLen Levy

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