Cohort study of forceps delivery and the risk of epilepsy in adulthood

American Journal of Obstetrics and Gynecology
Deirdre J MurphyAndrew Morris

Abstract

The purpose of this study was to investigate the relationship between forceps delivery and epilepsy in adulthood. Study design We conducted a cohort study of 21,441 births with record linkage to data from the Tayside Medicine Monitoring unit (MEMO) and Scottish morbidity records (SMR1). Delivery by forceps was not associated with epilepsy compared with all other deliveries, adjusted odds ratio (OR) 1.0 (95 % CI, 0.6-1.8). Epilepsy in adulthood was associated with a family history of epilepsy, adjusted OR 2.4 (95% CI, 1.7-3.2), increasing social deprivation, adjusted OR 1.1 for each Carstairs score (95% CI, 1.0-1.2), and male gender, adjusted OR 1.4 (95% CI, 1.0-1.8). Preterm birth was associated with an increased risk of epilepsy, adjusted OR 2.0 (95% CI, 1.2-3.2) but no other antenatal, intrapartum, or neonatal risk factors were identified. These findings do not suggest an association between forceps delivery and epilepsy in adulthood; however, preterm birth may be an important risk factor.

References

Jun 1, 1990·Archives of Disease in Childhood·P O PharoahL Rosenbloom
Jan 1, 1987·Epilepsia·K B Nelson, J H Ellenberg
Feb 1, 1996·British Journal of Obstetrics and Gynaecology·G I Meniru
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Aug 12, 2000·Pharmacotherapy·UNKNOWN American College of Clinical Pharmacy
Sep 7, 2002·Mental Retardation and Developmental Disabilities Research Reviews·Linda D Cowan
Nov 2, 2002·BMJ : British Medical Journal·Dominic C HeaneyJosemir W Sander
Nov 9, 2002·Epilepsia·Irene A W KotsopoulosJ André Knottnerus
Mar 26, 2003·Seizure : the Journal of the British Epilepsy Association·A S DaoudH El-Shanti

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Citations

Feb 19, 2016·European Journal of Public Health·M DelnordUNKNOWN Euro-Peristat Scientific Committee
Jan 15, 2014·American Journal of Obstetrics and Gynecology·Gemma C SharpJane E Norman
Jul 26, 2021·Seizure : the Journal of the British Epilepsy Association·Mercedes SarudianskyGuido Pablo Korman

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