Coincidental visualization of an atypical bronchial carcinoid on Tc-99m-sestamibi scan in Kallmann's syndrome

Annals of Nuclear Medicine
Zeynep YaparMehmet Inal

Abstract

We report a case of an atypical bronchial carcinoid showing sestamibi uptake. A 27-year-old man with Kallmann's syndrome and hyperparathyroidism had parathyroid scintigraphy with 99mTc-sestamibi. A focal uptake was observed on the right perihilar region, and this right perihilar mass was demonstrated on computed tomography and proved histologically to be an atypical bronchial carcinoid tumor. Factors which may explain the tumoral avidity for sestamibi are increased blood flow, transmembrane potentials of plasma and mitochondrial membranes and the relative number of mitochondria present in the cells of this carcinoid tumor. The importance of this case is the coincidence of an atypical carcinoid in a patient with significant failure of secondary sexual characteristics, right renal agenesis and bilateral anosmia associated with Kallmann's syndrome.

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Citations

Sep 17, 2008·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Hedieh K Eslamy, Harvey A Ziessman
Feb 1, 2011·Expert Opinion on Therapeutic Targets·Mehtap Cakir, Ashley Grossman
Apr 12, 2021·European Journal of Nuclear Medicine and Molecular Imaging·Petra Petranović OvčaričekFrederik Anton Verburg

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