Cokeromyces recurvatus in a cervical papanicolaou test: A case report of a rare fungus with a brief review of the literature

Diagnostic Cytopathology
Cherie PaquetteM Ruhul Quddus

Abstract

Here we report a rare case of Cokeromyces recurvatus in a Pap test in an asymptomatic pregnant patient. Each liquid-based Pap slide contained multiple rounded yeast-like forms measuring 10-30 µm including some profiles with peripheral small buds. The background had neither epithelial abnormality nor any significant inflammation. A positive silver stain aided in confirming a fungal organism. Rare fungi were considered including Paracoccidioides brasiliensis due to the 'mariner's wheel' morphology of forms with peripheral budding; however, the final report morphologically favored C. recurvatus which was subsequently confirmed by culture. This is the sixth report of C. recurvatus isolated at a gynecologic site. While C. recurvatus has been reported to cause invasive disease in immunocompromised patients at deep sites, in the gynecologic tract it has so far been reported as a non-pathogenic colonizer. Awareness of this organism and use of either culture or molecular diagnostics are important in avoiding misdiagnosis.

References

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Citations

Sep 29, 2020·Case Reports in Women's Health·M Luann Racher
May 19, 2021·Diagnostic Cytopathology·Neha KhaitanRaza S Hoda

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