Colchicine for steroid-resistant recurrent pericarditis in a child

Yeungnam University Journal of Medicine
Ju Hee ShinHee Joung Choi

Abstract

Recurrent pericarditis is rare in children and is considered idiopathic in most cases. Its course is chronic, and preventing recurrences is important for the patient's quality of life. Although a treatment strategy in pediatric recurrent pericarditis has not yet been established, non-steroidal anti-inflammatory drugs (NSAIDs) are the most common treatment for management of this condition, followed by corticosteroids, colchicine, immunosuppressive agents, immunoglobulins, and interleukin-1β receptor antagonists (e.g. anakinra). Herein, we report a case of recurrent pericarditis with pericardial effusion in a 5-year-old child who presented with fever and epigastric pain. He responded poorly to NSAIDs and corticosteroid therapy, but was successfully treated with colchicine.

References

Feb 24, 2010·Circulation·Massimo ImazioYehuda Adler
Oct 12, 2012·Pediatric Cardiology·Alessandra ScardapaneLuciana Breda
Oct 8, 2014·Pediatrics·M Rosa del FresnoJaime de Inocencio
Nov 9, 2014·Journal of the American Heart Association·Divya ShaktiJane W Newburger
Dec 18, 2014·The New England Journal of Medicine·Martin M LeWinter
Apr 17, 2016·Archives of Disease in Childhood·Samer AlabedAmanda Burls
Jul 29, 2016·Journal of Cardiovascular Medicine·Massimo ImazioAlberto Martini

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