PMID: 12770696May 29, 2003Paper

Cold and mechanical allodynia in both hindpaws and tail following thoracic spinal cord hemisection in rats: time courses and their correlates

Neuroscience Letters
Junesun KimHeung Sik Na

Abstract

We assessed (1) the time courses of cold and mechanical allodynia in both hindpaws and the tail, and (2) the relationship of the allodynia signs between different sites following spinal cord hemisection. Under enflurane anesthesia, rats were subjected to spinal hemisection at T13. The hemisected rats exhibited a significant increase in mechanical and cold allodynia signs of both hindpaws and the tail for 22-26 weeks postoperatively. In addition, mechanical allodynia signs were significantly correlated not only between the ipsilateral and the contralateral hindpaws, but also between the hindpaws and the tail. These results suggested that cold and mechanical allodynia developed extensively and lasted for a long time following spinal cord hemisection, and mechanical allodynia shown at different sites may be induced at least in part by common generating mechanisms.

References

Jun 1, 1992·The Clinical Journal of Pain·T E Balazy
Feb 1, 1995·Journal of Neurotrauma·D M BassoJ C Bresnahan

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Citations

Mar 26, 2011·Journal of Biomedicine & Biotechnology·Aya NakaeTakashi Mashimo
Jul 21, 2010·Experimental Neurology·Megan Ryan DetloffD Michele Basso
Jul 22, 2009·Neuroscience Letters·Junesun KimYoung Wook Yoon
Dec 8, 2009·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Ji-In JungYoung Wook Yoon
Jul 16, 2010·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Hyun Jeong KimJunesun Kim
Dec 25, 2009·Fundamental & Clinical Pharmacology·Amteshwar Singh JaggiNirmal Singh
May 8, 2018·Neurotherapeutics : the Journal of the American Society for Experimental NeuroTherapeutics·Rani Shiao, Corinne A Lee-Kubli

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