Cold atmospheric air plasma sterilization against spores and other microorganisms of clinical interest.

Applied and Environmental Microbiology
Tobias G KlämpflHans-Ulrich Schmidt

Abstract

Physical cold atmospheric surface microdischarge (SMD) plasma operating in ambient air has promising properties for the sterilization of sensitive medical devices where conventional methods are not applicable. Furthermore, SMD plasma could revolutionize the field of disinfection at health care facilities. The antimicrobial effects on Gram-negative and Gram-positive bacteria of clinical relevance, as well as the fungus Candida albicans, were tested. Thirty seconds of plasma treatment led to a 4 to 6 log(10) CFU reduction on agar plates. C. albicans was the hardest to inactivate. The sterilizing effect on standard bioindicators (bacterial endospores) was evaluated on dry test specimens that were wrapped in Tyvek coupons. The experimental D(23)(°)(C) values for Bacillus subtilis, Bacillus pumilus, Bacillus atrophaeus, and Geobacillus stearothermophilus were determined as 0.3 min, 0.5 min, 0.6 min, and 0.9 min, respectively. These decimal reduction times (D values) are distinctly lower than D values obtained with other reference methods. Importantly, the high inactivation rate was independent of the material of the test specimen. Possible inactivation mechanisms for relevant microorganisms are briefly discussed, emphasizing the imp...Continue Reading

References

Aug 1, 1997·Journal of Applied Microbiology·A D Russell
Apr 2, 1998·International Archives of Occupational and Environmental Health·J AngererA Krämer
Apr 2, 1998·Journal of Industrial Microbiology & Biotechnology·K Kelly-WintenbergP P Tsai
Jan 9, 1999·Clinical Microbiology Reviews·G McDonnell, A D Russell
Dec 9, 1993·Clinical Materials·I P MatthewsA H Samuel
May 27, 2003·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Sara E Cosgrove, Yehuda Carmeli
Aug 18, 2006·BMC Infectious Diseases·Axel KramerGünter Kampf
Mar 6, 2007·Trends in Microbiology·Peter Setlow
Jun 16, 2009·Journal of Microbiological Methods·Mrinal K BhattacharjeeOlumide T Ayandeji
May 26, 2010·Journal of the European Academy of Dermatology and Venereology : JEADV·J HeinlinS Karrer
Apr 13, 2011·Archives of Dermatology·Georg IsbaryWilhelm Stolz
Apr 3, 2012·Applied and Environmental Microbiology·Tim MaischJulia L Zimmermann

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Citations

May 21, 2014·Applied Microbiology and Biotechnology·Jan-Wilm Lackmann, Julia Elisabeth Bandow
Mar 19, 2014·International Journal of Antimicrobial Agents·Anne Mai-ProchnowKostya Ken Ostrikov
Feb 3, 2015·International Journal of Molecular Sciences·Krishna Priya ArjunanSylwia Ptasinska
Jan 20, 2016·Clinical Oral Investigations·Philipp PierdziochSaskia Preissner
Sep 1, 2015·Frontiers in Microbiology·Christopher J DoonaTerrance Leighton
Jun 26, 2014·Critical Reviews in Biotechnology·Sandra R B R SellaCarlos Ricardo Soccol
May 5, 2016·Advances in Therapy·Jesús Gay-MimbreraJuan Ruano
Oct 3, 2013·Medical Gas Research·Clotilde HoffmannJohn Zhang
Jul 13, 2016·ACS Applied Materials & Interfaces·Natthaporn KhamsenSiwapon Srisonphan
Sep 18, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Stefan HartwigJan Dirk Raguse
Dec 10, 2016·The Indian Journal of Medical Research·Devendra T MouryaPradip V Barde
Apr 6, 2018·Critical Reviews in Food Science and Nutrition·Xinyu LiaoTian Ding
Nov 20, 2014·Photochemical & Photobiological Sciences : Official Journal of the European Photochemistry Association and the European Society for Photobiology·Anita GollmerAndreas Späth
Jan 25, 2019·Critical Reviews in Food Science and Nutrition·Kexin ZhangBrijesh K Tiwari
Jun 15, 2017·Critical Reviews in Food Science and Nutrition·Haniye TolouieMaryam Hashemi

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