Cold plasma: a novel approach to treat infected dentin-a combined ex vivo and in vitro study

Clinical Oral Investigations
Philipp PierdziochSaskia Preissner

Abstract

The aim of this study was to evaluate the antimicrobial effect of cold plasma (CP) on infected dentin surfaces in vitro and ex vivo. To examine the effect of cold plasma on root surfaces, 24 root surfaces were infected with Streptococcus mitis. Specimens were randomly divided into three groups: Within the control group (C), root surfaces were rinsed with NaCl; root surfaces in the second group were additionally scaled and root planed (SRP), and in the third group, root surfaces were rinsed, scaled, root planed, and in addition, CP was applied (SRP + CP). To examine the effect of CP on root caries lesions (RCLs), 16 freshly extracted teeth with symmetrical carious lesions were equally divided into two groups. In the control group, carious lesions were treated with chlorhexidine (CHX), whereas CHX was applied in conjunction with CP in the test group (CHX + CP). For microbiological analysis, dentin samples were serially diluted and CFU counts were estimated after 24 h of incubation. Compared to C, mean CFU values for SRP and SRP + CP were significantly lower (p < 0.05). In addition, mean CFUs for SRP + CP were reduced to 0 and, therefore, significantly lower than SRP (2.98 log CFU/mL) alone (p = 0.000, Mann-Whitney U). Regarding R...Continue Reading

References

Sep 1, 1985·Journal of Oral Pathology·J S WefelJ R Heilman
Jun 4, 1999·Journal of Clinical Periodontology·M QuirynenD Van Steenberghe
Jan 25, 2002·The Journal of Prosthetic Dentistry·Chester W DouglassLarry Ostry
Dec 24, 2004·Journal of Dental Research·M De SoeteM Quirynen
Jan 6, 2006·Primary Dental Care : Journal of the Faculty of General Dental Practitioners (UK)·Aylin Baysan, Edward Lynch
Feb 28, 2009·Microbiology·Jonathan C JoaquinGraciela Brelles-Mariño
Jun 6, 2009·Monographs in Oral Science·K R EkstrandN B Pitts
Nov 10, 2009·Journal of Biomedical Optics·Juergen LademannOlaf Lademann
Nov 17, 2009·Journal of Medical Microbiology·Stefan RupfAxel Schindler
Apr 24, 2010·Archives of Gerontology and Geriatrics·María Morales-Suárez-VarelaAgustín Llopis-González
May 15, 2012·Applied and Environmental Microbiology·Tobias G KlämpflHans-Ulrich Schmidt
Aug 18, 2012·Advances in Dental Research·A W G Walls, J H Meurman
Jul 6, 2013·Materials Science & Engineering. C, Materials for Biological Applications·Seung Yun YangJin Kon Kim
Dec 21, 2013·Acta Odontologica Scandinavica·Jae-Hoon KimByeong-Hoon Cho
Mar 22, 2014·GMS Hygiene and Infection Control·Claudia Bender, Axel Kramer
Nov 16, 2014·Journal of Dental Research·R J Wierichs, H Meyer-Lueckel
Dec 4, 2014·Journal of Applied Oral Science : Revista FOB·Vinícius Rangel Geraldo-MartinsRegina Guenka Palma-Dibb
Dec 10, 2014·Biomolecules & Therapeutics·Beate HaertelUlrike Lindequist
Jan 20, 2015·Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG·Georg DaeschleinMichael Jünger
Jul 16, 2015·Clinical and Experimental Dermatology·S HasseK Masur
Aug 15, 2015·Clinical Plasma Medicine·Xiaoqing DongQingsong Yu

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