PMID: 6408950Jul 1, 1983Paper

Cold pressor test and variant angina

Angiology
T KawanoK Arakawa

Abstract

A transient complete coronary occlusion due to spasm was induced by the cold pressor test in a 51-year-old man with variant angina. Arteriography before the test revealed a normal left coronary artery and only minor irregularities of the mid-portion of the right coronary artery. Three minutes after cold stimulation, angina pectoris accompanied by ST-segment elevation was observed in lead II ECG. Simultaneous coronary arteriography during the attack showed a complete occlusion of the proximal right coronary artery due to spasm. The anginal attack together with spastic occlusion disappeared after administration of 0.8 mg of nitroglycerin. Thus, the cold pressor test can trigger coronary artery spasm and may even lead to a total occlusion in patients with variant angina. Individuals with variant angina may be subjected to additional risk when exposed to cold temperatures.

References

Dec 9, 1976·The New England Journal of Medicine·G H MudgeE Braunwald
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Citations

Feb 3, 2009·International Journal of Cardiology·Athanasios G ManolisCostas Dimopoulos
Jan 1, 1988·International Journal of Cardiology·T StefenelliH Sochor

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