Cold stress and light signals induce the expression of cold-inducible RNA binding protein (cirp) in the brain and eye of the Japanese treefrog (Hyla japonica)

Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
Kenkichi Sugimoto, Huijie Jiang

Abstract

Hibernation is an important physiological animal behavior. However, the molecular mechanism by which hibernation is regulated remains unknown. The Japanese treefrog (Hyla japonica) usually hibernates in the winter. Since this treefrog is an ectothermic animal, its hibernation is thought to be linked to the environmental temperature. In murine cells, gene expression for the cold-inducible RNA binding protein (cirp) is induced simply by cold stress. Therefore, it was hypothesized that the treefrog would also have increased expression of cirp during the hibernation season. In this report, we describe the cloning of the treefrog cirp gene and a quantitative analysis of its expression with real-time PCR. Like its homologs, treefrog cirp was found to be expressed in response to a cold stress, and its transcript was detectable in the brain, eye and ovary. Furthermore, we found that light signals could also induce the expression of cirp, and the total amount of cirp expression in both the brain and eye was significantly higher in December than in July. These results suggest that the expression of cirp in this treefrog is physiologically induced by environmental factors, such as cold stress or light signals.

References

Mar 1, 1996·Molecular and Cellular Neurosciences·A SehgalM Hunter-Ensor
Feb 21, 1998·Proceedings of the National Academy of Sciences of the United States of America·I ProvencioM D Rollag
May 8, 1998·Biochemical and Biophysical Research Communications·H NishiyamaJ Fujita
Sep 2, 1999·Cell and Tissue Research·R BhatiaL F Lemanski
May 19, 2000·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·T SaitoK J Mori
Aug 15, 2000·Microscopy Research and Technique·F E Anderson, C B Green
Nov 30, 2000·Nucleic Acids Research·K MatsumotoM Tsujimoto
Nov 24, 2001·Respiration Physiology·R G Boutilier
Mar 8, 2003·Journal of Neuroendocrinology·C B Green
Jul 13, 2004·The European Journal of Neuroscience·Joseph C BesharseJoseph Fogerty
Oct 26, 2005·The Journal of Experimental Biology·Jon P Costanzo, Richard E Lee
Jan 7, 2006·Developmental Dynamics : an Official Publication of the American Association of Anatomists·Radek SindelkaJirí Jonák
Apr 18, 2006·Cell·Noriaki KondoTakashi Ohtsu
Sep 21, 2007·Nature Reviews. Neuroscience·Erik D Herzog

❮ Previous
Next ❯

Citations

May 12, 2015·Biochemical and Biophysical Research Communications·Yuuki SanoYasutake Shimizu
May 6, 2016·Cellular and Molecular Life Sciences : CMLS·Xinzhou ZhuSven Wellmann
Aug 25, 2016·PloS One·Ignacio M LarrayozAlfredo Martínez
May 26, 2018·Scientific Reports·Amaël BorzéeYikweon Jang
Aug 22, 2017·Frontiers in Physiology·Frank Seebacher, Alexander G Little

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.