Colgi, Cajal and the Neuron Doctrine

Journal of the History of the Neurosciences
E G Jones

Abstract

Camillo Golgi and Santiago Ramon y Cajal shared the Nobel Prize in 1906 for their work on the histology of the nerve cell, but both held diametrically opposed views about the Neuron Doctrine which emphasizes the structural, functional and developmental singularity of the nerve cell. Golgi's reticularist views remained entrenched and his work on the nervous system did not venture greatly into new territories after its original flowering, which had greater impact than is now commonly credited. Cajal, by contrast, by the time he was awarded the Nobel Prize, was already breaking new ground with a new staining technique in the field of peripheral nerve regeneration, seeing the reconstruction of a severed nerve by sprouting from the proximal stump as another manifestation of the Neuron Doctrine. Paradoxically, identical studies were going on simultaneously in Golgi's laboratory in the hands of Aldo Perroncito, but the findings did not seem to influence Golgi's thinking on the Neuron Doctrine.

Citations

Jul 31, 2007·Brain Research Reviews·Edward G Jones
Apr 25, 2007·Brain Research Bulletin·Lawrence Kruger, Thomas S Otis
Apr 6, 2007·Brain Research Reviews·Lawrence Kruger
Jun 18, 2015·Frontiers in Neuroanatomy·Jairo A Rozo, Antonio Rodríguez-Moreno
Jul 12, 2014·Journal of Integrative Neuroscience·Riccardo Manzotti, Antonio Chella
Dec 20, 2007·Neurosurgery·Iver A Langmoen, Michael L J Apuzzo
Feb 18, 2017·Cellular and Molecular Life Sciences : CMLS·John BiancoFabienne Danhier
Mar 28, 2017·Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology·Günther K H Zupanc
Jun 18, 2017·Journal of the History of the Neurosciences·Jairo A RozoAntonio Rodríguez-Moreno
Feb 25, 2020·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Perry Zurn, Danielle S Bassett
Jul 14, 2018·Nature Reviews. Neuroscience·Danielle S BassettJoshua I Gold

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