PMID: 11918503Mar 29, 2002Paper

Collaborative care model to improve outcomes in major depression

The Annals of Pharmacotherapy
Denise M BoudreauNancy G Stevens

Abstract

To develop a pharmacist intervention to improve depression care and outcomes within a primary care setting. Pragmatic, randomized trial of a clinical pharmacist collaborative care intervention versus usual care in a busy, academic family practice clinic. Seventy-four patients diagnosed with a new episode of major depression and started on antidepressant medications were randomized to enhanced care (EC) or usual care (UC) groups. EC consists of a clinical pharmacist collaborating with primary care providers (PCPs) to facilitate education, initiation, and titration of acute-phase antidepressant treatment to monitor treatment adherence and to prevent relapse. Control patients receive UC by their PCP. The main end point is reduction of depression symptoms over time as measured by the Hopkins Symptom Checklist (SCL-20). Other outcomes include the Diagnostic and Statistical Manual of Mental Disorders, (DSM-IV) criteria for major depression, health-related quality of life measured by the Medical Outcomes Study Short Form 12 (SF-12), medication adherence, patient satisfaction, and healthcare utilization. The main end point and the cost of treating major depression will be used to estimate the cost-effectiveness of the collaborative car...Continue Reading

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Dec 2, 2006·The British Journal of Psychiatry : the Journal of Mental Science·Peter BowerAlex Sutton
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