Collagen and elastic content of abdominal skin after surgical weight loss.

Obesity Surgery
Simone C OrpheuMarcos C Ferreira

Abstract

Collapsed skin folds after bariatric weight loss are often managed by plastic procedures, but changes in dermal composition and architecture have rarely been documented. Given the potential consequences on surgical outcome, a prospective histochemical study was designed. The hypothesis was that a deranged dermal fiber pattern would accompany major changes in adipose tissue. Female surgical candidates undergoing postbariatric abdominoplasty (n=40) and never obese women submitted to control procedures (n=40) were submitted to double abdominal biopsy, respectively in the epigastrium and hypogastrium. Histomorphometric assessment of collagen and elastic fibers was executed by the Image Analyzer System (Kontron Electronic 300, Zeiss, Germany). Depletion of collagen, but not of elastic fibers, in cases with massive weight loss was confirmed. Changes were somewhat more severe in epigastrium (P=0.001) than hypogastrium (P=0.007). Correlation with age did not occur. (1) Patients displayed lax, soft skin lacking sufficient collagen fiber network. (2) Elastic fiber content was not damaged, and was even moderately increased in epigastrium; (3) Preoperative obesity negatively correlated with hypogastric collagen concentration; (4) Future st...Continue Reading

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Citations

Apr 20, 2010·Obesity Surgery·Shelly ChooMichele A Shermak
Jul 16, 2010·Obesity Surgery·Marco D'EttorreRoberto Bracaglia
Oct 7, 2014·Clinics in Plastic Surgery·Dirk F Richter, Alexander Stoff
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Aug 2, 2011·Obesity Surgery·Rodolpho Alberto BussolaroLydia Masako Ferreira
Jan 9, 2013·Obesity Surgery·Ali HalawiOssama Abbas
Jan 20, 2012·Aesthetic Plastic Surgery·Maíra MarquesMarcus Castro Ferreira
Jun 5, 2014·International Journal of Cosmetic Science·M MatsumotoH Sanada
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Oct 4, 2012·Acta Cirúrgica Brasileira·Eliziane Nitz de Carvalho CalviLydia Masako Ferreira
Nov 2, 2011·Acta Cirúrgica Brasileira·Eliziane Nitz de Carvalho CalviLydia Masako Ferreira
Jul 15, 2017·Journal of Plastic Surgery and Hand Surgery·Audrey PatouéNicolas Bertheuil
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Oct 16, 2019·Journal of the American Academy of Dermatology·Jordan RosenGil Yosipovitch
Jul 22, 2021·Revista do Colégio Brasileiro de Cirurgiões·Wilson Cintra JuniorRolf Gemperli

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