PMID: 6018647Mar 10, 1967Paper

Collagen-coated cellulose sponge: three dimensional matrix for tissue culture of Walker tumor 256

Science
J LeightonR L Kronenthal

Abstract

Three-dimensional growth of large populations of cells in vitro has been observed in the interstices of a matrix consisting of collagen-coated cellu lose sponge. The growth of Walker tumor 256 in this composite matrix is com pared with that found in a matrix composed of either cellulose sponge alone or collagen sponge alone. The composite matrix is superior to either one. Collagen coated cellulose sponge may provide a simple tool for the study of social interaction of cells in the formation of organized elementary tissue structures.

Citations

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