Collagen formula with Djulis for improvement of skin hydration, brightness, texture, crow's feet, and collagen content: A double-blind, randomized, placebo-controlled trial

Journal of Cosmetic Dermatology
Ping LinChen-Meng Kuan

Abstract

The efficacy of Djulis for skin care is currently based on cellular or animal models, and the clinical aspect is not in place. This clinical study is to investigate the synergistic effect of fish collagen and Djulis (Chenopodium formosanum Koidz.) for improvement of skin parameters. We used the combination of hydrolyzed collagen and Djulis to develop a new functional formula for skin improvement. Fifty volunteers were randomly allocated (in a 1:1 ratio) to the placebo or collagen drink group. Volunteers were required to consume a 50 mL of a collagen drink or placebo drink daily for 8 weeks. For measurements, the indexes of skin conditions were measured at the baseline and 4 and 8 weeks. The improvements of skin hydration, brightness, crow's feet, texture, wrinkles, pores, spots, and collagen content after 8 weeks in collagen group were 17.8%, 5.4%, 14.9%, 9.9%, 29.3%, 10.4%, 9.9%, and 22.3%, respectively. Noticeably, over 68% of subjects got improved for their skin parameters after 8-week intake of collagen drink. The improvement levels indicated competitive skin improvement effects in comparison with previous studies. This clinical study demonstrates the synergistic effect of fish collagen and Djulis (the main components) for ...Continue Reading

References

Jul 14, 1995·The Journal of Biological Chemistry·M Karin
Nov 20, 2002·Archives of Dermatology·Gary J FisherJohn J Voorhees
Aug 31, 2006·Yonsei Medical Journal·Ju Hee LeeKwang Hoon Lee
Sep 14, 2006·Journal of Nutritional Science and Vitaminology·Naoya MatsudaKazushige Takehana
Aug 12, 2008·Clinics in Dermatology·Paolo U Giacomoni
Apr 9, 2009·Bioscience, Biotechnology, and Biochemistry·Midori TanakaYoshihiro Nomura
Feb 4, 2010·Plastic and Reconstructive Surgery·Zoe Diana Draelos
Feb 11, 2011·Journal of Agricultural and Food Chemistry·Pi-Jen TsaiChin-Yen Chen
Jun 8, 2012·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Jae Woo ChoiSang Woong Youn
Mar 8, 2013·Dermato-endocrinology·Eleni PapakonstantinouGeorge Karakiulakis
Mar 8, 2013·Dermato-endocrinology·Ruta GancevicieneChristos C Zouboulis
Jun 5, 2013·Journal of Food Science and Technology·K JayathilakanA S Bawa
May 20, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Alexandra Amaro-OrtizJohn A D'Orazio
Oct 25, 2014·Clinical Interventions in Aging·Maryam Borumand, Sara Sibilla
Jul 18, 2017·Journal of Dermatological Science·Yinjuan WangPhilippe Humbert
Aug 15, 2017·Nutrients·Juliet M PullarMargreet C M Vissers

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Citations

Jul 16, 2021·Journal of Cosmetic Dermatology·Ya-Ping TsengChia-Hua Liang
Aug 28, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Patrícia Maria Berardo Gonçalves Maia CamposElodie Bouvret

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