Collagen tube conduits in peripheral nerve repair: a retrospective analysis.

Hand : Official Journal of the American Association for Hand Surgery
Kirk J Wangensteen, Loree K Kalliainen

Abstract

A chart review was conducted of all patients receiving NeuraGen® conduits from 2002 to 2007 at Regions Hospital, a level I trauma center. Ninety-six patients underwent 126 repairs using NeuraGen® conduits, and 64 patients were seen in follow-up. Repairs were largely of upper extremity sensory nerves but six were repairs of nerves elsewhere in the body. There were no intra-operative complications, but there were two minor postoperative complications and one postoperative pulmonary embolus. Forty of 126 repairs were lost to follow-up. Twenty-six of 126 repairs had follow-up with quantitative testing of nerve recovery (2-point discrimination, Semmes-Weinstein, or EMG testing), with 35% reporting improvement and 31% going on to a revision operation. Sixty of 126 repairs had qualitative testing performed (subjective or objective reporting of sensation or motor function), with 45% reporting improvement and 5% going on to a revision operation. Patients who went on to revision surgery were more likely to have undergone quantitative evaluation of sensation. Overall, sensory recovery was in the 35-45% range in our experience. Our results indicate that NeuraGen® collagen conduits can be used safely throughout the body.

Associated Clinical Trials

May 28, 2019·Julia AV Nuelle

References

Mar 1, 1990·Plastic and Reconstructive Surgery·S E Mackinnon, A L Dellon
Jun 1, 2005·The Journal of Hand Surgery·Mariëtta J O E BertleffJean-Phillipe A Nicolai
Oct 14, 2006·Neurosurgery·Burkhard SchlosshauerNektarios Sinis
Dec 14, 2006·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·J LohmeyerP Mailänder
Sep 3, 2008·The Journal of Hand Surgery·Brandon D BushnellTerry M Messer
Oct 14, 2008·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Anthony Farole, Basem T Jamal
Nov 28, 2008·Journal of Reconstructive Microsurgery·Jörn A LohmeyerPeter Mailänder

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Citations

Mar 1, 2012·Histochemistry and Cell Biology·Stefan Hübner, Athina Efthymiadis
Jul 6, 2013·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Marcel F Meek, J Henk Coert
May 7, 2011·Hand Surgery : an International Journal Devoted to Hand and Upper Limb Surgery and Related Research : Journal of the Asia-Pacific Federation of Societies for Surgery of the Hand·Azal JalgaonkarGanapathyraman Mani
Oct 24, 2013·Plastic and Reconstructive Surgery·Neil F SachanandaniThomas H Tung
Feb 11, 2014·Expert Review of Neurotherapeutics·Víctor CarrielMaria Cornelissen
Jul 31, 2013·Hand Clinics·Michael Y LinRanjan Gupta
Sep 2, 2014·Advanced Drug Delivery Reviews·Matthew T WolfStephen F Badylak
Dec 25, 2012·The Journal of Hand Surgery·Adina HaugErwin Kunesch
Oct 30, 2012·The Journal of Hand Surgery·Mickey S ChoGregory M Buncke
Oct 19, 2010·Progress in Neurobiology·Ronald DeumensGary A Brook
Aug 2, 2014·Journal of Tissue Engineering and Regenerative Medicine·Víctor CarrielMiguel Alaminos
Oct 23, 2015·BioMed Research International·Aikeremujiang Muheremu, Qiang Ao
Jul 17, 2015·Journal of Tissue Engineering and Regenerative Medicine·Víctor CarrielMiguel Alaminos
Aug 23, 2012·Journal of Controlled Release : Official Journal of the Controlled Release Society·Aaron TanAlexander M Seifalian
Jun 17, 2015·Journal of Hand and Microsurgery·Mark Henry
Apr 21, 2016·Hand Clinics·Bauback Safa, Gregory Buncke
Dec 3, 2014·The Journal of Hand Surgery·Anjan P Kaushik, Warren C Hammert
Sep 13, 2016·International Journal of Molecular Sciences·Salazar JonesXiaofeng Jia
Jul 9, 2016·Hand : Official Journal of the American Association for Hand Surgery·Michael SosinRamon A DeJesus
Mar 1, 2013·Foot & Ankle International·John S GouldSuresh Cheppalli
Mar 14, 2017·Journal of Biomaterials Science. Polymer Edition·Francesco PaduanoMarco Tatullo
Apr 12, 2017·The Journal of Hand Surgery, European Volume·J L HuberH-H Homann
Oct 17, 2015·Journal of Biomedical Materials Research. Part a·Wei WangKazuo Takakuda
Nov 23, 2017·Annals of Plastic Surgery·Samer Bassilios HabrePetros Konofaos
Jul 22, 2018·Neurologia i neurochirurgia polska·Patrycja ChrząszczWiesław Marcol
Nov 7, 2013·Biofabrication·Christopher M OwensCheryl M Heesch
Oct 16, 2019·Nanomedicine·Igor D LuzhanskyMikhail Y Berezin
Apr 16, 2020·Journal of Tissue Engineering and Regenerative Medicine·Jesús Chato-AstrainVictor Carriel
Jun 26, 2020·Advanced Healthcare Materials·Mary KasperChristine E Schmidt
Feb 17, 2015·World Journal of Clinical Cases·David J GerthSeth R Thaller
Oct 14, 2017·World Journal of Stem Cells·Sara Sayad Fathi, Arash Zaminy
Dec 14, 2018·Wiener medizinische Wochenschrift·Tim KornfeldChristine Radtke
Dec 24, 2018·Journal of Biomedical Science·Rossana BoniAndrew N Clarkson

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