PMID: 6987989Feb 1, 1980Paper

Collagen types synthesized in dermal fibroblast cultures from patients with early progressive systemic sclerosis

Arthritis and Rheumatism
R E GayE J Miller

Abstract

Fibroblast cultures were established by explant culture from upper and lower dermis of 7 normal donors and 10 patients with early progressive systemic sclerosis (PSS). Antibodies against collagens containing the A and B chains, collagens which occur largely in vascular structures, were isolated and used for immunofluorescence studies. Cultures from lower PSS dermis accumulated significantly more of these collagens than fibroblast cultures from upper PSS dermis or cultures from upper or lower dermis of normal skin. These data indicate that the collagens containing the A and B chains in early PSS lesions are produced by cells of vascular origin and support the concept that alterations in vascular tissue play a prominent role in the pathogenesis of PSS.

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Citations

Jan 1, 1991·Archives of Dermatological Research·K TakeharaY Ishibashi
Jun 27, 1997·International Journal of Cardiology·E KazzamK Caidahl
Apr 1, 1981·Collagen and Related Research·E C LeRoy
Jul 1, 1981·Collagen and Related Research·S GayE J Miller
Jul 1, 1982·Collagen and Related Research·H Birkedal-HansenR Gay
Sep 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·M A HaralsonE J Miller
Feb 1, 1982·Proceedings of the National Academy of Sciences of the United States of America·E C LeRoyG K Sherer
Feb 1, 1982·The Journal of Cell Biology·A Martinez-HernandezE J Miller
Jan 1, 1983·The Journal of Experimental Medicine·M S HibbsA H Kang
Jun 23, 1984·British Medical Journal·M I Jayson
Jan 12, 2005·Arthritis Research & Therapy·Wan-Uk KimChul-Soo Cho
Jul 11, 2002·Biological Chemistry·Nicolette SoharIstvan Sohar
Jan 1, 1995·International Reviews of Immunology·J Varga, R I Bashey
Sep 25, 2010·Journal of Plastic, Reconstructive & Aesthetic Surgery : JPRAS·Harun SeyhanRaymund E Horch
Mar 25, 2004·The American Journal of Pathology·Yoshihide AsanoKunihiko Tamaki
May 1, 1982·The British Journal of Dermatology·K HerrmannI Lohrisch
Mar 1, 1984·International Journal of Dermatology·E B LeeL A Diaz
Jan 1, 1985·Annals of the New York Academy of Sciences·T KriegR Fleischmajer
Mar 1, 1983·The British Journal of Dermatology·M KitabatakeH Maeda
Aug 1, 1986·Zentralblatt für Veterinärmedizin. Reihe A·D TroyerH W Leipold
Nov 1, 2005·Clinical Biochemistry·Nicolette SoharHelga Hammer
Oct 30, 1981·Biochemical and Biophysical Research Communications·M Z AbedinJ B Weiss
May 31, 2018·Advanced Healthcare Materials·Yanling ZhouJiang Chang
Apr 1, 1986·The American Journal of Anatomy·L T SmithJ A Madri
Mar 1, 1992·Arthritis and Rheumatism·S GayR E Gay
Oct 1, 1990·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·B StrasnickR A Mickel
Aug 1, 1980·Arthritis and Rheumatism·S GayE F Miller
Nov 1, 1980·Arthritis and Rheumatism·S L StoverL L Gale
Aug 1, 1983·Seminars in Arthritis and Rheumatism·M E Nimni
Jul 1, 1994·Clinics in Dermatology·J VargaJ Uitto

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