Collateral innervation of the medial and lateral prefrontal cortex by amygdaloid, thalamic, and brain-stem neurons

The Journal of Comparative Neurology
Martin Sarter, H J Markowitsch

Abstract

The distribution of the afferents to the rat's prefrontal cortex originating in the thalamic mediodorsal nucleus and the amygdala was investigated with two fluorescent tracers. Special emphasis was laid on detecting the loci of neurons which project via axonal collaterals into both lateral and medial portions of the prefrontal cortex. It was found that a high number of neurons of the anterior portion of the basolateral amygdaloid nucleus terminate via collaterals in both the medial and lateral subfields of the prefrontal cortex. On the other hand, only a small number of mediodorsal thalamic cells were found to project to both sides of the prefrontal hemisphere via bifurcating axonal collaterals. These cells were situated exclusively in the lateral part of the medial segment of the mediodorsal nucleus. The majority of both thalamic and amygdaloid neurons with bifurcating axons originate from subregions whose cells innervate primarily the medial prefrontal cortex. In brain-stem, neurons of the nucleus raphé dorsalis also project via collaterals to the medial and lateral prefrontal regions. Furthermore, neurons of the dorsal and ventral premamillary nuclei, the lateral mamillary nucleus, the ventral tegmental area of Tsai, and the...Continue Reading

References

Jan 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Feb 15, 1979·The Journal of Comparative Neurology·C B SaperW M Cowan
Mar 1, 1979·Behavioral and Neural Biology·C E Rosenkilde
Apr 14, 1978·Experimental Brain Research·M BentivoglioE Tempesta
Jan 1, 1979·Experimental Neurology·W W Kaelber, T B Smith
Jun 15, 1979·Experientia·J Artieda, J Ullán
Apr 15, 1977·The Journal of Comparative Neurology·J E Krettek, J L Price
Jul 23, 1976·Brain Research·H J Markowitsch, M Pritzel
Apr 15, 1976·The Journal of Comparative Neurology·R M Beckstead
Jan 1, 1972·Brain, Behavior and Evolution·V B Domesick
Feb 1, 1969·Brain Research·V B Domesick
Jan 1, 1972·Brain, Behavior and Evolution·C M Leonard
Oct 1, 1974·Journal of Comparative and Physiological Psychology·B KolbR K Singh
Feb 15, 1974·Brain Research·J E Krettek, J L Price
Aug 1, 1974·Journal of Comparative and Physiological Psychology·A J NonnemanB Kolb
Jan 1, 1971·Archives of Neurology·K E Livingston, A Escobar
Jun 1, 1968·Journal of Comparative and Physiological Psychology·L Pellegrino

Citations

Jan 1, 1988·Neuroscience and Behavioral Physiology·A A OrlovA P Shutov
May 1, 1987·Brain Research·R D Oades, G M Halliday
Dec 14, 1990·Behavioural Brain Research·A S BatuevA P Shutov
Jun 10, 1991·Neuroscience Letters·A GranatoD Minciacchi
Sep 1, 1986·Brain Research Bulletin·M D Cassell, D J Wright
Sep 1, 1986·Brain Research Bulletin·A J McDonald, J L Culberson
Jun 1, 1991·Brain Research Bulletin·L J Freedman, M D Cassell
Nov 6, 2003·Neuroscience and Biobehavioral Reviews·Christian A Heidbreder, H J Groenewegen
Mar 5, 2003·Hormones and Behavior·Rachel E BowmanVictoria N Luine
Jul 17, 1999·Brain Research. Brain Research Reviews·T van GroenJ M Wyss
Aug 29, 1998·Behavioural Brain Research·G G BerntsonJ T Cacioppo
Oct 8, 2008·Development and Psychopathology·Christopher S Monk
Aug 5, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Julie M BrooksJohn P Bruno
Jul 12, 2012·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Julie M BrooksJohn P Bruno
Mar 6, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Vinay ParikhMartin Sarter
Dec 12, 2003·Proceedings of the National Academy of Sciences of the United States of America·Gerd PoeggelKatharina Braun
Feb 1, 1988·The International Journal of Neuroscience·J A Jesberger, J S Richardson
Mar 1, 1986·The International Journal of Neuroscience·Martin Sarter
Dec 1, 1985·The International Journal of Neuroscience·Martin Sarter, H J Markowitsch
Mar 1, 1984·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·H J Markowitsch
Mar 1, 1985·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Martin Sarter, H J Markowitsch
Jan 23, 2013·Journal of Chemical Neuroanatomy·Stephanie B LinleyRobert P Vertes
Jun 11, 2011·Journal of Chemical Neuroanatomy·Maria WaselusElisabeth J Van Bockstaele
May 26, 2009·Behavioural Brain Research·Frédéric ChauveauDaniel Béracochéa
Dec 1, 2015·Frontiers in Behavioral Neuroscience·Thomas F Giustino, Stephen Maren
May 19, 2012·The Journal of Comparative Neurology·Sun Jung Bang, Kathryn G Commons

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