Collateral Status in Ischemic Stroke: A Comparison of Computed Tomography Angiography, Computed Tomography Perfusion, and Digital Subtraction Angiography

Journal of Computer Assisted Tomography
Frans KauwMax Wintermark

Abstract

To compare assessment of collaterals by single-phase computed tomography (CT) angiography (CTA) and CT perfusion-derived 3-phase CTA, multiphase CTA and temporal maximum-intensity projection (tMIP) images to digital subtraction angiography (DSA), and relate collateral assessments to clinical outcome in patients with acute ischemic stroke. Consecutive acute ischemic stroke patients who underwent CT perfusion, CTA, and DSA before thrombectomy with occlusion of the internal carotid artery, the M1 or the M2 segments were included. Two observers assessed all CT images and one separate observer assessed DSA (reference standard) with static and dynamic (modified American Society of Interventional and Therapeutic Neuroradiology) collateral grading methods. Interobserver agreement and concordance were quantified with Cohen-weighted κ and concordance correlation coefficient, respectively. Imaging assessments were related to clinical outcome (modified Rankin Scale, ≤ 2). Interobserver agreement (n = 101) was 0.46 (tMIP), 0.58 (3-phase CTA), 0.67 (multiphase CTA), and 0.69 (single-phase CTA) for static assessments and 0.52 (3-phase CTA) and 0.54 (multiphase CTA) for dynamic assessments. Concordance correlation coefficient (n = 80) was 0.08...Continue Reading

References

Apr 14, 2007·Annals of Neurology·Jessica C TanMax Wintermark
Oct 1, 2011·Stroke; a Journal of Cerebral Circulation·Marc RiboCarlos A Molina
Dec 3, 2011·AJNR. American Journal of Neuroradiology·F McVerryK W Muir
Jun 14, 2013·Stroke; a Journal of Cerebral Circulation·Ewoud J SmitMathias Prokop
Mar 13, 2014·Journal of Neuroradiology. Journal De Neuroradiologie·Edouard MartinonAdrien Chavent
May 23, 2015·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Charity J Morgan, Inmaculada Aban
Dec 15, 2015·Journal of Neurointerventional Surgery·Fatih SekerMirko Pham
Dec 15, 2015·Stroke; a Journal of Cerebral Circulation·María Hernández-PérezJosep Munuera
Jul 16, 2016·AJNR. American Journal of Neuroradiology·I G H JansenUNKNOWN MR CLEAN investigators (www.mrclean-trial.org)
Sep 2, 2017·The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques·Colin CasaultBijoy K Menon

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Citations

Jun 19, 2021·Journal of Neurointerventional Surgery·Mohammad AnadaniUNKNOWN ETIS Registry Investigators

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