Collectins in urinary tract and kidney diseases.

International Urology and Nephrology
Yongfang QinFengqi Hu

Abstract

The innate immune system serves as the frontline defense against invading pathogens and initiates an inflammatory response to microorganisms. Collectins are C-type lectins that are structurally characterized by a collagen-like sequence and a carbohydrate recognition domain. Moreover, they are widely expressed throughout the body and are involved in the innate immunity against a variety of pathogens, regulating inflammation, and protecting the lungs from pathogens. Recently, two classical collectins, surfactant protein A (SP-A) and surfactant protein D (SP-D), as well as novel collectin 11, were found present in urinary tract tissues. They are increasingly recognized as key players in activating the humoral arm of innate immunity and host defense in urinary tract and kidney diseases, although their biological features, functions, and mechanisms in this regard remain largely unclear. In this review, we aim to integrate results reported by ourselves and others to summarize and gain a better understanding of the functions of collectins (SP-A, SP-D, and collectin 11) in urinary tract and kidney diseases.

References

Jul 8, 2000·Kidney International·A K CheungA S Levey
Jan 6, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·J D SchillingS J Hultgren
May 23, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·J R Bourbon, B Chailley-Heu
Jun 8, 2001·The Journal of Immunology : Official Journal of the American Association of Immunologists·M YoshidaJ A Whitsett
Jul 13, 2002·The American Journal of Medicine·Betsy Foxman
Sep 24, 2002·The Journal of Immunology : Official Journal of the American Association of Immunologists·R William VandivierKelly E Greene
May 17, 2003·The Journal of Clinical Investigation·Huixing WuFrancis X McCormack
Jan 5, 2005·Nature Reviews. Immunology·Jo Rae Wright
Jan 3, 2006·American Journal of Physiology. Heart and Circulatory Physiology·Grith L SorensenUffe Holmskov
Sep 20, 2006·The Journal of Immunology : Official Journal of the American Association of Immunologists·Cécilia ChassinAlain Vandewalle
Dec 21, 2006·Microbiology and Immunology·Hiroyuki KeshiNobutaka Wakamiya
May 11, 2007·Cellular Microbiology·Yoshio KurokiChiaki Nishitani
Nov 28, 2007·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·Wataru MotomuraNobutaka Wakamiya
Dec 21, 2007·Journal of the American Society of Nephrology : JASN·Sharon M Moe, Neal X Chen
Mar 25, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Gary D SnyderNeal L Weintraub
Jun 6, 2008·Neonatology·Henk P HaagsmanEdwin J A Veldhuizen
Nov 15, 2008·PLoS Biology·Chang-Jiang GuoAndrew J Gow
Apr 3, 2009·Kidney International·Xue-Ru WuTung-Tien Sun
Oct 6, 2009·Advances in Experimental Medicine and Biology·Patrick WatersTaruna Madan
Mar 17, 2010·Recent Patents on Anti-infective Drug Discovery·Shanjana Awasthi
Apr 29, 2010·Innate Immunity·Barbara A SeatonRichard Mendelsohn
Jun 5, 2010·Shock·Giselle Martins GonçalvesNiels Olsen Saraiva Câmara
Jun 18, 2010·American Journal of Physiology. Renal Physiology·Hidetake KuriharaTatsuo Sakai
Sep 25, 2010·Journal of the American Society of Nephrology : JASN·Michael Zeisberg, Eric G Neilson
Oct 20, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Soren HansenUffe Holmskov
Oct 28, 2010·Nature Reviews. Nephrology·Tilman B Drüeke, Ziad A Massy
Sep 7, 2011·Journal of Biochemistry·Takayuki YoshizakiNobutaka Wakamiya
Jan 15, 2013·Journal of Cardiovascular Medicine·Fangyi XieGenshan Ma
Aug 21, 2013·Nature Reviews. Immunology·J Simon C Arthur, Steven C Ley
Sep 17, 2013·The American Journal of Pathology·Niki PrakouraAristidis S Charonis
Jan 30, 2014·Thorax·Michelle C WilliamsUNKNOWN Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints (ECLIPSE) investigators
Apr 8, 2014·The Journal of Medical Investigation : JMI·Hisatsugu GotoYasuhiko Nishioka
Aug 5, 2014·Current Pediatric Reviews·Anastasia K Ketko, Steven M Donn
Feb 2, 2015·Journal of Pediatric Surgery·Ryuta SakaHiroomi Okuyama

❮ Previous
Next ❯

Related Concepts

Related Feeds

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.