Collision cross section measurements for biomolecules within a high-resolution FT-ICR cell: theory

Physical Chemistry Chemical Physics : PCCP
Dan GuoWei Xu

Abstract

In this study, an energetic hard-sphere ion-neutral collision model was proposed to bridge-link ion collision cross section (CCS) with the image current collected from a high-resolution Fourier transform ion cyclotron resonance (FT-ICR) cell. By investigating the nonlinear effects induced by high-order electric fields and image charge forces, the energetic hard-sphere collision model was validated through experiments. Suitable application regions for the energetic hard-sphere collision model, as well as for the conventional Langevin and hard-sphere collision models, were also discussed. The energetic hard-sphere collision model was applied in the extraction of ion CCSs from high-resolution FT-ICR mass spectra. Discussions in the present study also apply to FT-Orbitraps and FT-quadrupole ion traps.

References

Oct 13, 1998·Mass Spectrometry Reviews·A G MarshallG S Jackson
Jul 3, 2003·Mass Spectrometry Reviews·Julia Laskin, Jean H Futrell
Mar 1, 2005·Journal of the American Society for Mass Spectrometry·C Richard Arkin, D A Laude
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Jan 21, 2015·Journal of Mass Spectrometry : JMS·Muyi HeWei Xu

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Citations

Sep 1, 2015·Physical Chemistry Chemical Physics : PCCP·Ting JiangWei Xu
May 26, 2016·Journal of the American Society for Mass Spectrometry· AnupriyaDavid V Dearden
May 2, 2016·Journal of Magnetic Resonance·Daniel K ParkRaymond Laflamme
Jul 13, 2017·Journal of the American Society for Mass Spectrometry·Eric T DziekonskiScott A McLuckey
Apr 3, 2018·Analytical Chemistry·James D SandersJennifer S Brodbelt
Dec 21, 2021·Journal of the American Society for Mass Spectrometry·Brigham L PopeDavid V Dearden

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