Abstract
A colistin-resistant Escherichia coli isolate from a commercial poultry farm in China carried two colistin resistance genes, mcr-1 and variant of mcr-3, in an IncP plasmid. The variant of the mcr-3 gene, named mcr-3.11, encoded two amino acid substitutions compared with the mcr-3 gene. A novel genetic structure, ISKpn40-mcr-3-dgkA-ISKpn40, might be the key element mediating the translocation of mcr-3 through the formation of a circular form. The mcr-1 and mcr-3 genes, which are colocated on a plasmid, might pose a huge threat to public health.
References
Oct 11, 2002·Journal of Bacteriology·Markus Haas, Bodo Rak
Jun 25, 2004·Nucleic Acids Research·Aron Marchler-Bauer, Stephen H Bryant
Nov 16, 2010·Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi·Po-Ren HsuehLee-Jene Teng
Feb 1, 2011·Bioinformatics·Mitchell J SullivanScott A Beatson
Aug 10, 2011·BMC Genomics·Nabil-Fareed AlikhanScott A Beatson
Sep 10, 2015·Microbiology Spectrum·Michael ChandlerGuy Duval-Valentin
Nov 26, 2015·The Lancet Infectious Diseases·Yi-Yun LiuJianzhong Shen
Jul 16, 2016·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Basil Britto XavierSurbhi Malhotra-Kumar
Nov 30, 2016·Antimicrobial Agents and Chemotherapy·Feifei ZhaoZhiyong Zong
Jan 12, 2017·The Journal of Antimicrobial Chemotherapy·Ruichao LiSheng Chen
Jun 29, 2017·MBio·Wenjuan YinYang Wang
Aug 12, 2017·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·Alessandra CarattoliChiara Francesca Magistrali
Aug 30, 2017·Antimicrobial Agents and Chemotherapy·Zhuoren LingJianzhong Shen
Sep 20, 2017·Antimicrobial Agents and Chemotherapy·Bi-Hui LiuHong-Ning Wang
Sep 30, 2017·The Journal of Antimicrobial Chemotherapy·Maria BorowiakBurkhard Malorny
Oct 4, 2017·Antimicrobial Agents and Chemotherapy·Lu LiuZhiyong Zong
Nov 29, 2017·The Journal of Antimicrobial Chemotherapy·Marisa HaenniRichard Bonnet
Dec 6, 2017·Antimicrobial Agents and Chemotherapy·Xiaoming WangYang Wang
Citations
Feb 23, 2019·The Journal of Antimicrobial Chemotherapy·Ruichao LiLi Bai
Jun 19, 2019·Antimicrobial Agents and Chemotherapy·Pei ZhangRuichao Li
Feb 1, 2020·Microbial Genomics·Cheryll M SiaTimothy J Dallman
Dec 19, 2019·Frontiers in Microbiology·Linda HadjadjJean-Marc Rolain
Jul 28, 2018·The Journal of Antimicrobial Chemotherapy·Sally R PartridgeBasil Britto Xavier
Dec 17, 2020·Frontiers in Veterinary Science·David Ortega-ParedesChristian Vinueza-Burgos
Jul 15, 2020·Antimicrobial Agents and Chemotherapy·Yu-Zhang HeJian Sun
Apr 5, 2021·International Journal of Food Microbiology·Phong Quoc LeShinji Yamasaki
Apr 12, 2021·Molecular Biology Reports·Nadheema Hammood HusseinJumaah Dakel Hussein
May 21, 2021·The Journal of Antimicrobial Chemotherapy·Milan S StosicMarianne Sunde