Colonoscopic features and malignant potential of sessile serrated adenomas: comparison with other serrated lesions and conventional adenomas

Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland
Keisuke KawasakiTakayuki Matsumoto

Abstract

Sessile serrated adenomas/polyps (SSA/Ps) have been proposed as precursors of colorectal cancer. The aims of this investigation were to compare the endoscopic findings of SSA/Ps with those of other serrated lesions and to compare the histological findings of SSA/Ps with those of conventional adenomas. We retrospectively reviewed colonoscopy records at our institution from 1984 to 2013 and identified cases of endoscopically or surgically resected conventional adenomas and serrated lesions, including SSA/Ps, hyperplastic polyps (HPs) and traditional serrated adenomas (TSAs). The colonoscopic findings of SSA/Ps were compared with those of the other two serrated lesions and histological findings were compared among all groups of lesions. There were 79 HPs in 68 patients, 77 SSA/Ps in 63 patients, 167 TSAs in 145 patients and 6324 conventional adenomas in 4129 patients. The inverted type and flat-elevated type were more frequent among SSA/Ps than among the other two types of serrated lesions. Magnifying colonoscopy revealed that a round and open pit pattern, expanded crypt openings and varicose microvascular vessels were more frequently observed among SSA/Ps than among the other types. The incidence of high-grade dysplasia or carcin...Continue Reading

References

Apr 1, 1979·Diseases of the Colon and Rectum·H S CooperG Marks
Jun 1, 1990·The American Journal of Surgical Pathology·T A Longacre, C M Fenoglio-Preiser
Sep 1, 1988·The New England Journal of Medicine·B VogelsteinJ L Bos
Apr 1, 1985·The American Journal of Surgical Pathology·L H Sobin
Oct 1, 1968·The British Journal of Surgery·B C Morson
Mar 1, 1996·Gastroenterology·E Torlakovic, D C Snover
Aug 29, 2002·Gastroenterology·Jeremy R JassBarbara A Leggett
Dec 28, 2002·The American Journal of Surgical Pathology·Emina TorlakovicJahn M Nesland
May 16, 2003·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Carolyn BariolRobyn L Ward
Oct 1, 1958·Annals of Surgery·J S SPRATTC A MOYER
Sep 6, 1962·The New England Journal of Medicine·B CASTLEMAN, H I KRICKSTEIN
Apr 21, 2004·European Journal of Gastroenterology & Hepatology·Kageaki KuribayashiTetsuji Takayama
Mar 2, 2005·Archives of Internal Medicine·Otto S LinRichard A Kozarek
Jan 6, 2007·Histopathology·M J Mäkinen
Dec 29, 2007·The American Journal of Surgical Pathology·Emina Emilia TorlakovicDale C Snover
Mar 25, 2008·Modern Pathology : an Official Journal of the United States and Canadian Academy of Pathology, Inc·Scott R OwensShih-Fan Kuan
Jun 16, 2010·Journal of Clinical Pathology·Richard H LashChristopher M Schuler
Sep 28, 2010·Human Pathology·Dale C Snover
Sep 23, 2011·Hepato-gastroenterology·Hiroshi KashidaMasatoshi Kudo
Jan 12, 2012·The American Journal of Gastroenterology·Tomoaki KimuraMinoru Toyota
Jun 20, 2012·The American Journal of Gastroenterology·Douglas K RexJames Church
Sep 13, 2012·World Journal of Gastroenterology : WJG·Shinya IshigookaFumio Itoh
Jul 4, 2013·European Journal of Gastroenterology & Hepatology·Yutaka NakaoHisao Tajiri
Oct 15, 2013·Gastrointestinal Endoscopy·Makoto KutsukawaShigeharu Hamatani
Aug 5, 2014·Journal of Gastroenterology and Hepatology·Takeshi YamashinaHiroyasu Iishi
Oct 2, 2014·Journal of Gastroenterology·Toshio UraokaKazuhide Yamamoto

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Sep 30, 2016·World Journal of Gastroenterology : WJG·Rajvinder SinghAlastair Burt
Oct 27, 2020·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Leonardo Zorron Cheng Tao PuRajvinder Singh

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