PMID: 6107410Sep 20, 1980Paper

Colonoscopy and the detection of dysplasia in patients with longstanding ulcerative colitis

Lancet
R J DickinsonA T Axon

Abstract

The role of colonoscopy in the surveillance of patients with ulcerative colitis for dysplasia was investigated in 43 patients with longstanding disease extending proximally beyond the splenic flexure. The examination was well tolerated and no complications were recorded. Dysplasia was found in 9 patients in one or more biopsies and was severe in 2, moderate in 1, and mild in 6. Both the patients with severe dysplasia had a carcinoma at subsequent operation. Colonoscopy may allow complete examination of the colon and biopsy of suspicious lesions and, since dysplasia may spare the rectum, colonoscopy with biopsy is a desirable component of any surveillance programme of the at-risk colitic.

References

Dec 1, 1978·The British Journal of Surgery·W N BakerS O Aylett
Oct 1, 1975·Gut·R H Teague, A E Read
Apr 1, 1974·Gut·H E MyrvoldC Ahrén
Jan 1, 1980·Scandinavian Journal of Gastroenterology·S GranqvistT Thorgeirsson
May 1, 1964·Cancer·M B GOLDGRABER, J B KIRSNER

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Citations

Oct 1, 1989·Nutrition Reviews·J B Mason
Nov 23, 2000·Diseases of the Colon and Rectum·S R GorfineI Kreel
Nov 1, 1986·Diseases of the Colon and Rectum·D C AllenC H Calvert
Oct 3, 1991·The New England Journal of Medicine·D K Podolsky
Jan 1, 1985·Journal of Clinical Pathology·D C AllenP C Pyper
Nov 1, 1987·Journal of Clinical Pathology·S A DundasJ C Underwood
Jun 1, 1991·Photochemistry and Photobiology·R Richards-KortumM S Feld
Oct 1, 1988·Histopathology·M F DixonG T Williams
Mar 1, 1987·Scandinavian Journal of Gastroenterology·M GronowitzC Ahrén
Oct 29, 2000·The American Journal of Gastroenterology·J A Eaden, J F Mayberry
Mar 1, 1988·Scandinavian Journal of Gastroenterology·J RutegårdK G Janunger
Jan 1, 1990·Scandinavian Journal of Gastroenterology. Supplement·R H Riddell
Jul 1, 1982·Acta Pathologica, Microbiologica, Et Immunologica Scandinavica. Section A, Pathology·C A RubioP Slezak
Oct 1, 1989·Digestive Diseases and Sciences·B A LashnerS B Hanauer
May 1, 1984·Diseases of the Colon and Rectum·C A RubioC Hammarberg

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