Colonoscopy Surveillance and Management of Dysplasia in Inflammatory Bowel Disease

Current Treatment Options in Gastroenterology
Tonya KaltenbachRoy Soetikno

Abstract

Patients with long-standing ulcerative colitis (UC) and extensive Crohn's disease (CD) colitis have a high risk of colorectal cancer (CRC) and are recommended to undergo surveillance with colonoscopy. Recent data highlights their increased risk of CRC compared to the general population despite colonoscopy surveillance. The proportion of IBD patients diagnosed with interval CRC within 6 to 36 months following a clearing colonoscopy was 15 %. Optimizing colonoscopy surveillance methods is important. Studies have demonstrated that the best endoscopic surveillance strategy to detect dysplasia is chromoendoscopy with surface application of dyes to enhance the mucosal visualization and that visible dysplasia should be endoscopically resected. In this chapter we will summarize the optimal surveillance and management techniques for colorectal dysplasia in IBD patients.

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Citations

Mar 12, 2019·International Journal of Colorectal Disease·Sameen KhalidUdayakumar Navaneethan
Nov 10, 2020·Clinics in Colon and Rectal Surgery·Makoto Nishimura

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