PMID: 8601888Mar 1, 1996Paper

Color-flow Doppler-assisted duplex imaging fails to detect ulceration in high-grade internal carotid artery stenosis

Journal of Vascular Surgery
M SitzerH Steinmetz

Abstract

Pathoanatomic studies suggest that plaque surface disruption, particularly ulceration, plays a key role in the destabilization of internal carotid artery stenosis. Until now, the validity of color-flow Doppler-assisted duplex imaging in detecting such pathoanatomically defined plaque surface abnormalities is unclear. We prospectively determined the interobserver reliability and validity of detecting plaque ulceration by means of preoperative color-flow Doppler-assisted duplex imaging in 43 consecutive patients with high-grade (> or = 70%) internal carotid artery stenosis, comparing these ultrasonographic findings with pathoanatomic evaluations of the corresponding endarterectomy specimens. Interobserver reliabilities for detecting carotid plaque ulceration were kappa= 0.57 for ultrasonography and kappa = 0.82 for the pathologic reference method. Color-flow Doppler-assisted duplex imaging (observer consensus) failed to detect pathoanatomically defined ulceration (chi square = 0.43; p = 0.51). Likewise, sensitivity, specificity, overall accuracy, and positive predictive value were poor (33%, 67%, 56%, and 46%, respectively). We conclude from our data that color-flow Doppler-assisted duplex imaging is not a reliable or valid means...Continue Reading

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Citations

Oct 4, 2005·Neuroimaging Clinics of North America·Javier M RomeroMichael H Lev
Nov 21, 2008·Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging·Isabelle MomjianRoman Sztajzel
Apr 5, 2002·Journal of Vascular Surgery·Aaron TroyerUNKNOWN Assessment of Carotid Stenosis by Comparison with Endarterectomy Plaque Trial Investigators
Oct 27, 2010·Current Problems in Cardiology·Gerrit L ten KateArend F L Schinkel
Apr 25, 2012·AJR. American Journal of Roentgenology·Mutsuko MurakiTakeshi Kashiwaba
Mar 10, 2012·Stroke; a Journal of Cerebral Circulation·Isabelle Momjian-MayorRoman F Sztajzel
Jan 29, 2009·Physics in Medicine and Biology·Bernard ChiuAaron Fenster
Feb 8, 2006·Neurosurgery·Masaru HondaTomayoshi Hayashi
Aug 29, 2013·Expert Review of Cardiovascular Therapy·Patricia Martinez-Sanchez, Andrei V Alexandrov
Feb 6, 2017·Insights Into Imaging·Vasileios RafailidisAfroditi Charitanti-Kouridou

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