Color vision in two observers with highly biased LWS/MWS cone ratios

Vision Research
E MiyaharaE Baron

Abstract

Two sisters, heterozygous carriers for congenital X-linked protanopia, were diagnosed as normal trichromats by the Rayleigh match on the anomaloscope. The heterozygous state was established by molecular analysis of their visual pigment genes. The normal color match establishes that the spectral sensitivities of their long-wavelength-sensitive (LWS) and middle-wavelength-sensitive (MWS) cone visual photopigments are within normal variability. Their FM 100-hue test error scores were low, demonstrating superior chromatic discrimination. Heterochromatic flicker photometric (HEP) spectral sensitivities were like those of protanopes. The estimated LWS/MWS cone ratios from the HFP data were 0.09/1 and 0.03/1, compared with ratios in the range of 0.6/1 to 10/1 for typical normal trichromats. Measurements of chromatic grating acuity on chromatically selective backgrounds were performed to study the cone mosaic. The data were consistent with a sparsity of LWS cones. Both protan carriers showed normal spectral sensitivities for all three cone types under cone isolating chromatic adaptation and normal three-peaked curves for increment thresholds on a white pedestal. Hue estimation, run on one carrier was normal. The equilibrium yellow locu...Continue Reading

References

Sep 1, 1979·Journal of the Optical Society of America·A L Nagy, R M Boynton
Jan 1, 1979·Vision Research·J D Moreland, J Kerr
Sep 1, 1977·Journal of the Optical Society of America·J Pokorny, V C Smith
Jan 1, 1977·Vision Research·C R Ingling
Jul 1, 1976·Journal of the Optical Society of America·P E King-Smith, D Carden
Jan 1, 1991·Vision Research·M F WesnerV C Smith
Feb 1, 1990·Journal of the Optical Society of America. A, Optics and Image Science·B E Schefrin, J S Werner
Jan 1, 1989·Vision Research·R L VimalS K Shevell
Oct 1, 1989·Journal of the Optical Society of America. A, Optics and Image Science·J PokornyM Lutze
Jan 1, 1988·Vision Research·H R WilsonJ Pokorny
Nov 1, 1988·Journal of the Optical Society of America. A, Optics and Image Science·K LaxarB R Wooten
Jan 1, 1987·Vision Research·R S SnelgarM O Scase
Jan 1, 1974·Kybernetik·R F Quick
Feb 1, 1972·American Journal of Ophthalmology·M IkedaM Urakubo
Jun 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·G Wald
Jan 1, 1968·Journal of the Optical Society of America·M Ikeda, M Urakubo
May 1, 1968·The Journal of Physiology·D G Green
Nov 1, 1966·Journal of Experimental Psychology·C E Sternheim, R M Boynton
Nov 22, 1983·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·H J DartnallJ D Mollon
Dec 1, 1984·The Journal of Physiology·A M DerringtonP Lennie
Jan 1, 1982·Annual Review of Psychology·J D Mollon
Jun 1, 1993·Journal of the Optical Society of America. A, Optics and Image Science·J PokornyV C Smith
Jul 1, 1993·Vision Research·G Jordan, J D Mollon
May 1, 1993·Vision Research·R L De Valois, K K De Valois
Oct 1, 1991·The European Journal of Neuroscience·B. B. Boycott, H. Wässle
May 28, 1954·The Journal of Physiology·G S BRINDLEY
Aug 1, 1955·American Journal of Optometry and Archives of American Academy of Optometry·I SCHMIDT
Aug 1, 1959·American Journal of Ophthalmology·R A CRONE
Nov 1, 1960·Journal of the Optical Society of America·G V BEKESY
Aug 1, 1961·American Journal of Ophthalmology·M L RUBIN
Jan 1, 1949·Documenta Ophthalmologica. Advances in Ophthalmology·W S STILES

❮ Previous
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Citations

Sep 12, 2006·Visual Neuroscience·Gerald H Jacobs, Gary A Williams
Sep 12, 2006·Visual Neuroscience·I J MurrayD J McKeefry
Dec 21, 2007·Visual Neuroscience·Hana LangrováAnne Kurtenbach
Jul 5, 2008·Visual Neuroscience·J L BarburM Neitz
Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·A PanorgiasI J Murray
Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·N K ChallaA Panorgias
Aug 10, 2001·Psychonomic Bulletin & Review·K A JamesonL M Wasserman
Oct 11, 2007·Network : Computation in Neural Systems·Michael A WebsterShernaaz M Webster
Apr 9, 2001·Vision Research·P PearsonR L Fellman
May 13, 2006·Vision Research·S M HoodG Jordan
Jan 20, 1999·Vision Research·P M KainzJ Neitz
May 29, 2000·Vision Research·S OtakeC M Cicerone
Jan 24, 2002·Vision Research·Gerald H JacobsWen Hsiung Li
Nov 10, 2005·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Gokhan MalkocMichael A Webster
Sep 7, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·M A WebsterV E Raker
Aug 30, 2001·Optometry and Vision Science : Official Publication of the American Academy of Optometry·A Lang, G W Good
Feb 24, 1999·Nature·A Roorda, D R Williams
Sep 24, 2004·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·David Bimler, John Kirkland
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·J KremersL T Sharpe
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·D H BrainardG H Jacobs
Mar 9, 2000·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·S Otake, C M Cicerone
May 30, 2019·Physiological Reviews·Wallace B Thoreson, Dennis M Dacey
Apr 4, 2014·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Elise W Dees, Rigmor C Baraas
Apr 4, 2014·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Helen Le SueurGabriele Jordan
Mar 15, 2016·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Li Zhaoping, Joseph Carroll
Mar 15, 2016·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Joris VincentSteven L Buck
Nov 3, 2004·Visual Neuroscience·I J MurrayA Schild
Feb 15, 2012·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Jan Kremers, Gobinda Pangeni
Nov 24, 2015·Annual Review of Vision Science·David H Brainard
May 9, 2019·I-Perception·Kanthi A WidayatiKowa Koida
Apr 23, 2020·Annual Review of Vision Science·Joel Pokorny, Vivianne C Smith
May 14, 2020·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·Michael A Webster
Jun 20, 2020·Perception·Brian K Foutch, Carl J Bassi

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