PMID: 11331924May 2, 2001Paper

Colorectal cancer complicating Crohn's disease

Canadian Journal of Gastroenterology = Journal Canadien De Gastroenterologie
H J Freeman

Abstract

Some earlier studies have indicated that patients with inflammatory bowel disease, especially those with long-standing and extensive ulcerative colitis, have an increased risk of colorectal cancer. Moreover, others in tertiary care centres have suggested that patients with Crohn's disease also have a higher risk of colorectal cancer. Canadian data on colorectal cancer in Crohn's disease appear to be limited. For this investigation, a single clinician database of 877 patients with Crohn's disease was used. Altogether, there were six patients with colorectal cancer (ie, overall rate of 0.7%). All of these patients were men with an initial diagnosis of Crohn's disease established at a mean age of approximately 28 years, with either ileocolonic disease or colonic disease alone, but not with ileal disease alone. Although there was a predominance of women in the overall study population (ie, 56.1%), no women developed colorectal cancer. The clinical behaviour of Crohn's disease was classified as nonstricturing in all six patients with colorectal cancer, but in two patients, Crohn's disease was complicated by a perirectal abscess or a fistula. All cancers were located in the rectum and were diagnosed 30 years, 22 years, seven years, 1...Continue Reading

Citations

Sep 1, 2005·International Journal of Colorectal Disease·Tamás ZágoniZsolt Tulassay
Mar 20, 2008·World Journal of Gastroenterology : WJG·Hugh-James Freeman
Sep 26, 2008·Inflammatory Bowel Diseases·Hugh J Freeman
Jul 16, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Cesare RuffoloImerio Angriman
Dec 15, 2010·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Mike Georg LaukoetterMatthias Bruewer
Jan 10, 2012·Diseases of the Colon and Rectum·Maurice W M D LutgensUNKNOWN Dutch Initiative on Crohn and Colitis
Aug 20, 2003·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·R I SjödahlJ D Söderholm
Feb 20, 2007·Diseases of the Colon and Rectum·Alexander C von RoonParis P Tekkis
Sep 5, 2013·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·T M Connelly, W A Koltun
Feb 16, 2010·Inflammatory Bowel Diseases·Pamela M O'ConnorAndre G Buret
May 4, 2013·Expert Review of Gastroenterology & Hepatology·Tara M Connelly, Walter A Koltun
Nov 20, 2004·Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen·A D RinkK-H Vestweber
Sep 5, 2014·Inflammatory Bowel Diseases·Zain KassamPaul L Beck
Jul 19, 2006·International Journal of Colorectal Disease·Sabine KerstingChristian F Krieglstein
Sep 28, 2002·European Journal of Gastroenterology & Hepatology·Sunil A SonwalkarPierre J Guillou
Nov 27, 2019·The Journal of Surgical Research·Christopher C TaylorNader N Massarweh
Nov 4, 2004·Gastroentérologie Clinique Et Biologique·Axèle ChampaultYves Panis

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