Colorectal Cancer: Cost-effectiveness of Colonoscopy versus CT Colonography Screening with Participation Rates and Costs

Radiology
Miriam P van der MeulenMarjolein van Ballegooijen

Abstract

Purpose To compare the cost-effectiveness of computed tomographic (CT) colonography and colonoscopy screening by using data on unit costs and participation rates from a randomized controlled screening trial in a dedicated screening setting. Materials and Methods Observed participation rates and screening costs from the Colonoscopy or Colonography for Screening, or COCOS, trial were used in a microsimulation model to estimate costs and quality-adjusted life-years (QALYs) gained with colonoscopy and CT colonography screening. For both tests, the authors determined optimal age range and screening interval combinations assuming a 100% participation rate. Assuming observed participation for these combinations, the cost-effectiveness of both tests was compared. Extracolonic findings were not included because long-term follow-up data are lacking. Results The participation rates for colonoscopy and CT colonography were 21.5% (1276 of 5924 invitees) and 33.6% (982 of 2920 invitees), respectively. Colonoscopy was more cost-effective in the screening strategies with one or two lifetime screenings, whereas CT colonography was more cost-effective in strategies with more lifetime screenings. CT colonography was the preferred test for willing...Continue Reading

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Citations

Mar 21, 2020·The American Journal of Gastroenterology·Amir-Houshang OmidvariIris Lansdorp-Vogelaar
Mar 17, 2021·British Journal of Cancer·Lindy M KregtingInge M C M de Kok
May 15, 2020·Academic Radiology·David H BallardGary J Whitman
Jun 22, 2021·European Journal of Cancer Care·Elizabeth LemmonEva J A Morris
Nov 7, 2020·Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences·Minerva H Zhou, Akash P Kansagra

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