Colorectal cancer presenting as bone metastasis

Journal of Cancer Research and Therapeutics
M C Suresh BabuSuparna Ajit Rao

Abstract

Bone metastasis is a rare site of metastasis, seen in only 3.7-11% of clinical cases. Isolated bone involvement has been reported very rarely in literature. Moreover, the patients who have bone metastasis at presentation are even rare. To discuss the demographic characteristics, carcinoembryonic antigen (CEA) levels, pattern of bone involvement, and their correlation with survival in patients of colorectal cancer that have bone metastasis at the time of presentation. Retrospectively, tumor registry was analyzed for the cases of colorectal cancer presenting with bone metastasis between 2008 and 2013. Survival curves were generated by Kaplan-Meier method and analyzed using the log-rank test. Ten such patients were identified (male:female = 7:3) of the total 410 patients. Median age was 41 years (22-50 years). All patients were Conclusions: In this study, the patients of colorectal cancer presenting with bone metastasis were of male sex and younger age. The factors that were associated with reduced survival were extraosseous and liver involvement.

References

Mar 1, 1979·Diseases of the Colon and Rectum·J L HoehnC S Avecilla
May 1, 1978·Diseases of the Colon and Rectum·S Besbeas, M W Stearns
Oct 1, 1995·Journal of Gastroenterology·M KatohS Fukuchi
Dec 29, 1999·Diseases of the Colon and Rectum·R KanthanS C Kanthan
Jan 1, 1950·Cancer·H L ABRAMSN GOLDSTEIN
Aug 9, 2007·World Journal of Surgical Oncology·Nishith Nb PatelPuthcode N Haray
Oct 28, 2011·World Journal of Surgical Oncology·Jill K OnestiAlan T Davis
Dec 12, 2012·Surgery Today·Sei-ichiro JimiShigeaki Takeda

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Citations

Jul 30, 2020·Cancers·Isabella GiganteMaria Notarnicola
Jul 30, 2020·International Journal of Surgery Case Reports·Isabel Maria Furtado Duarte Lobo GonçalvesLaura Jimenez Alvarez

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